Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans [PDF]
Calcific aortic valve disease is a progressive condition that shares some common pathogenic features with atherosclerosis. Transforming growth factor-ß1 is a recognized mediator of atherosclerosis and is expressed in aortic valve lesions.
Ballinger, M+6 more
core +1 more source
Miniaturized Devices for On‐the‐Spot Generation of Small‐Diameter Vascular Grafts
An intracorporeal extrusion device is developed for on‐the‐spot generation of vascular grafts with tunable diameters spanning from 1 to 6 mm. The device uses biomimetic polymers and light, to promptly obtaining biocompatible and high‐burst pressure‐resistant grafts.
Deyanira Hernandez‐Sanchez+11 more
wiley +1 more source
Objective: After transcatheter aortic valve replacement, the mean transvalvular pressure gradient indicates the effectiveness of the therapy. The objective is to develop artificial intelligence to predict the post–transcatheter aortic valve replacement ...
Anoushka Dasi, BS+5 more
doaj +1 more source
Follow-Up Report of Patients With Moderate Aortic Valve Regurgitation After Cardiac Surgery [PDF]
Background: The appropriateness of aortic valve surgery for patients with moderate aortic valve regurgitation undergoing coronary artery bypass graft (CABG), mitral valve replacement (MVR), or both is uncertain.
Arezou Zoroufian, MD+6 more
doaj +1 more source
Possible predicative role of electrical risk score on transcatheter aortic valve replacement outcomes in older patients. preliminary data [PDF]
Background:Transcatheter aortic valve replacement (TAVR) is an effective procedure capable to change the natural history of the degenerative aortic valve stenosis.
DI IORIO, Claudia+9 more
core +1 more source
One‐Step Covalent Biofunctionalization of Tubular Constructs Enabled by Surface‐Embedded Radicals
Uniform covalent biofunctionalization of tubular constructs is achieved in one step using surface‐embedded radicals generated by a novel plasma immersion ion implantation (PIII) technology. This scalable, solvent‐free technology advances bioengineered tubes for tissue engineering and implant applications.
Anyu Zhang+12 more
wiley +1 more source
Surgical Complexity and Outcome of Patients Undergoing Re-do Aortic Valve Surgery
ObjectivesRe-do aortic valve surgery carries a higher mortality and morbidity compared with first time aortic valve replacement (AVR) and often requires concomitant complex procedures.
Mario Petrou+6 more
doaj +1 more source
Advanced Microfluidics for Single Cell‐Based Cancer Research
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro+10 more
wiley +1 more source
Long-term survival after aortic valve replacement with the Mitroflow bioprosthesis : a comparative study [PDF]
Background Recent case reports of early structural degeneration of the Mitroflow valve have cast doubts on the suitability of this bioprosthesis, particularly in the smaller sizes, and in younger patients.
Camilleri, Liberato, Manche, Alexander
core +1 more source
Cardiac papillary fibroelastomas: A 10-year single-center surgical experience and long-term echocardiographic follow-up study [PDF]
Aims. Limited contemporary data are available on the clinical and echocardiographic outcomes after surgery for cardiac papillary fibroelastoma (CPF). The aim of this study was to review the clinical manifestations, pathological characteristics, surgical ...
Brát, Radim+3 more
core +1 more source