A missense TGFB2 variant p.(Arg320Cys) causes a paradoxical and striking increase in aortic TGFB1/2 expression. [PDF]
, 2016 Loeys-Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder with a range of cardiovascular, skeletal, craniofacial and cutaneous manifestations.
AM Bertoli-Avella +22 more
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Pregnancy‐Related Aortic Dissection—A Rare Complication of Pregnancy
Clinical Case Reports, Volume 13, Issue 1, January 2025.ABSTRACT Patients with pregnancy‐related aortic dissections should be transferred to high‐volume aortic centers for management. Malperfusion syndromes from acute type A aortic dissections appear to have better outcomes with thoracic endovascular repair before definitive surgical repair.
Mohammad Baseem Shaikh +3 more
wiley +1 more source
Molecular insights into bicuspid aortic valve development and the associated aortopathy
AIMS Molecular Science, 2017 Bicuspid Aortic valve (BAV) is one of the most common congenital cardiac malformations with a prevalence of 1–2% in the general population. Patients with BAV have a 9-fold increased risk of developing serious secondary complications including stenosis ...
Nikhita Bolar +3 more
doaj +1 more source
Innominate truncal and arch blowout with left hemiparesis and right hemothorax followed by delayed cheese-wire perforation of innominate graft [PDF]
, 2013 We present the case of a 68 year old Caucasian woman, in extremis, with left hemiparesis and right hemothorax, in hypovolemic shock, secondary to a blow-out of a large penetrating ulcer at the junction of innominate trunk and aortic arch.
Pankaj Kaul, Rodolfo Paniagua
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Clinically relevant variants identified in thoracic aortic aneurysm patients by research exome sequencing [PDF]
, 2016 Thoracic aortic aneurysm (TAA) is a genetically heterogeneous disease involving subclinical and progressive dilation of the thoracic aorta, which can lead to life-threatening complications such as dissection or rupture.
Hinton, Robert B. +4 more
core +1 more source
Methodist DeBakey Cardiovascular JournalThoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome.
Valeria E. Duarte +2 more
doaj +1 more source
Role of Echocardiography Before Transcatheter Aortic Valve Implantation (TAVI) [PDF]
, 2016 Aortic stenosis (AS) is the most common primary valve disorder in the elderly with an increasing prevalence; transcatheter aortic valve implantation (TAVI) has become an accepted alternative to surgical aortic valve replacement (AVR) in the high risk or ...
Badiani, S, Bhattacharyya, S, Lloyd, G
core +1 more source
Frontiers in Physiology, 2019 The bicuspid aortic valve, a kind of heart disease that comes from parents, has been paid attention around the world. Although most bicuspid aortic valve (BAV) patients will suffer from some complications including aortic stenosis, aortic regurgitation ...
Tianshu Liu +15 more
doaj +1 more source
Comparison of Efficacy and Safety of Transcatheter Aortic Valve Implantation in Patients With Bicuspid Versus Tricuspid Aortic Valves [PDF]
, 2017 Bicuspid aortic valve (BAV) stenosis has been considered a contraindication to transcatheter aortic valve implantation (TAVI). The aim of this study is to compare the efficacy and safety of TAVI in patients with BAV with those with tricuspid aortic valve
Cedars, A. +5 more
core +1 more source
In search of genetic modifiers that explain the phenotypic variability in SMAD3-related aortopathy [PDF]
, 2023 Joe Davis Velchev +5 more
openalex +1 more source