Results 71 to 80 of about 5,408 (223)

Clinical, Echocardiographic, and Socioeconomic Predictors of Progression and Outcomes in Patients With Moderate Aortic Stenosis

Echocardiography, Volume 42, Issue 12, December 2025.
A comprehensive model integrating clinical, imaging, and socioeconomic data improves prediction of disease progression and outcomes in moderate aortic stenosis, supporting a shift toward personalized assessment and management. ABSTRACT Background Despite increased awareness of its clinical consequences, personalized risk stratification in patients with
Alex D'Amico, Paul Nona, Loren Wagner, Miguel R. Sotelo, Chris Rogers, Navin Nanda, Julian Booker, Efstathia Andrikopoulou   +7 more
wiley   +1 more source

Use of a targeted, combinatorial next-generation sequencing approach for the study of bicuspid aortic valve [PDF]

, 2014
BACKGROUND: Bicuspid aortic valve (BAV) is the most common type of congenital heart disease with a population prevalence of 1-2%. While BAV is known to be highly heritable, mutations in single genes (such as GATA5 and NOTCH1) have been reported in few ...
David Newsom, Don Corsmeier, Elizabeth M Bonachea, Gloria Zender, Kim L McBride, Peter White, Sara Fitzgerald-Butt, Vidu Garg   +7 more
core   +2 more sources

Dissecting Shared Genetic Architecture of Thoracic Aortic Aneurysm and Aortic Related Traits and Identifying SplA/Ryanodine Receptor Domain and SOCS Box Containing 1 Involved in Smooth Muscle Phenotype Switching and Cell Senescence Through Alternative Splicing

The FASEB Journal, Volume 39, Issue 22, 30 November 2025.
The flowchart of the study. BAPN, β‐aminopropionitrile; FUMA, Functional Mapping and Annotation; GO, Gene Ontology; GWAS, genome‐wide association study; KEGG, Kyoto encyclopedia of genes and genomes; LDSC, LD score regression; MR‐JTI, mendelian randomization joint‐tissue imputation; MTAG, multi‐trait analysis of GWAS; siRNA, small interfering RNA ...
Qingyang Song, Tongxin Chu, Quan Liu, Rennan Weng, Huayang Li, Mengya Liang, Zhongkai Wu   +6 more
wiley   +1 more source

Aortopathy in the 7q11.23 microduplication syndrome [PDF]

American Journal of Medical Genetics Part A, 2014
The 7q11.23 microduplication syndrome, caused by the reciprocal duplication of the Williams‐Beuren syndrome deletion region, is a genomic disorder with an emerging clinical phenotype. Dysmorphic features, congenital anomalies, hypotonia, developmental delay highlighted by variable speech delay, and autistic features are characteristic findings ...
Parrott, Ashley, James, Jeanne, Goldenberg, Paula, Hinton, Robert B., Miller, Erin, Shikany, Amy, Aylsworth, Arthur S., Kaiser-Rogers, Kathleen, Ferns, Sunita J., Lalani, Seema R., Ware, Stephanie M.   +10 more
openaire   +3 more sources

MRI Assessment of Energy Loss Within the Thoracic Aorta and Its Impact on Cardiac Function in Fontan Patients After Aortic Reconstruction

Journal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1397-1407, November 2025.
ABSTRACT Background In Fontan patients undergoing aortic reconstruction, concerns regarding the impact of aortic function on ventricular function exist. Purpose 4D Flow MRI was used to compare energy loss (EL) within the thoracic aorta in patients with and without aortic reconstruction. Study Type Retrospective case control.
Yujiro Ide, Dominik Gabbert, Jan Hinnerk Hansen, Anselm Uebing, Inga Voges   +4 more
wiley   +1 more source

Balloon‐Expandable Versus Self‐Expanding Valves in Bicuspid Aortic Stenosis: Insights From the SWEDEHEART Registry

Catheterization and Cardiovascular Interventions, Volume 106, Issue 4, Page 2336-2347, October 1, 2025.
ABSTRACT Background Transcatheter aortic valve replacement (TAVR) is increasingly used in patients with bicuspid aortic valve (BAV) stenosis, but there is limited comparative data on balloon‐expandable (BEV) versus self‐expanding valves (SEV) in this population. Aim To compare clinical and hemodynamic outcomes between BEVs and SEVs in patients with BAV
Antros Louca, Joakim Sundström, Araz Rawshani, Henrik Hagström, Magnus Settergren, Stefan James, Sasha Koul, Kristofer Skoglund, Dan Ioanes, Sebastian Völz, Anna Myredal, Oskar Angerås, Petur Petursson, Truls Råmunddal   +13 more
wiley   +1 more source

Wall Shear Stress Directional Abnormalities in BAV Aortas: Toward a New Hemodynamic Predictor of Aortopathy?

Frontiers in Physiology, 2018
The bicuspid aortic valve (BAV) generates wall shear stress (WSS) abnormalities in the ascending aorta (AA) that may be responsible for the high prevalence of aortopathy in BAV patients.
Janet Liu, Jason A. Shar, Philippe Sucosky   +2 more
doaj   +1 more source

Type F congenital quadricuspid aortic valve: A very rare case diagnosed by 3-dimenional transoesophageal echocardiography [PDF]

, 2014
Congenital quadricuspid aortic valve (QAV) is a rare cardiac anomaly. Several different anatomical variations of a quadricuspid aortic valve have been described.
Cooke JC, Davia JE, Di Pino A, Feldman BJ, Fernández B, Gulyasy B, Hazlyna Kamaruddin, Holt NF, Hurwitz LE, Olson LJ, Pankaj Garg, Rachel Orme, Scrofani R, Takeda N, Tang YF, Tutarel O, Victoria Watt, Ward C   +17 more
core   +2 more sources

Bentall Procedure: A Standard for Managing Large Aortic Root Aneurysm in Marfan Syndrome

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT The Bentall procedure remains a reliable surgical solution for treating aortic root aneurysms in patients with Marfan syndrome. It significantly reduces the risk of catastrophic events such as rupture or dissection while offering durable and favorable long‐term results.
Syed Mohsin Raza Bukhari, Muhammad Ans, Muhammad Bilal Iqbal, Jalil Abbas, Ishrat Fatima, Mohsin Raza   +5 more
wiley   +1 more source

Long‐Term Durability of Transcatheter Aortic Valves in Patients With Bicuspid Aortic Stenosis

Catheterization and Cardiovascular Interventions, Volume 106, Issue 3, Page 1746-1757, September 1, 2025.
ABSTRACT Background Data concerning the long‐term durability of transcatheter aortic valves (TAVs) in patients with bicuspid aortic stenosis (AS) are lacking. Aims The study aims to report data on long‐term valve durability following transcatheter aortic valve replacement (TAVR) in bicuspid AS.
Yuheng Jia, Annette Maznyczka, Mauro Boiago, Arif Khokhar, Daijiro Tomii, Antoinette Neylon, Pauline Danthine, Thomas Levesque, Paul Bamford, Stefan Toggweiler, Federico Moccetti, Jarkko Piuhola, Marianna Adamo, Mauro Massussi, Alfonso Ielasi, Matteo Montorfano, Giulia Costa, Martin Swaans, Daniël C. Overduin, Clément Servoz, Caterina Gandolfo, Ingibjörg Jóna Guðmundsdóttir, Stefano Salizzoni, Joanna J. Wykrzykowska, Kees H. van Bergeijk, Andrea Buono, Tau Hartikainen, Stephane Noble, Darren Mylotte, Stephen Brecker, Ahmed Thabit, Antonio Mangieri, Pierfrancesco Agostoni, Matjaž Bunc, Maarten Vanhaverbeke, Johan Bosmans, Hélène Eltchaninoff, Azeem Latib, Daniel Blackman, Nicolas M. Van Mieghem, Yuan Feng, Won‐Keun Kim, Thomas Pilgrim, Bernard Prendergast, Didier Tchétché, Mao Chen, Ole De Backer   +46 more
wiley   +1 more source