Results 81 to 90 of about 4,070 (210)

Cardiovascular disease burden in thoracic aortopathy [PDF]

A strong correlation exists between abdominal aortopathy and atherosclerosis. In thoracic aortopathy however, the prevalence of atherosclerosis and its role in the etiology of thoracic aortopathy remained unknown.
Dolmaci, O.B.
core  

Potential mechanistic linkage between NOTCH1 variants, miR-145 expression and bicuspid aortopathy.

, 2018
Potential mechanistic linkage between NOTCH1 variants, miR-145 expression and bicuspid aortopathy.
Martin Ungelenk (3385412), Tanja Zeller (112753), Ingo Kurth (499801), Evaldas Girdauskas (5570918), Niklas Neumann (5570921), Hermann Reichenspurner (123790), Johannes Petersen (4055716)   +6 more
core   +1 more source

Novel MYH11 Splice Site Variant Causing Exon Skipping in a Family With Thoracic Aortic Aneurysms and Dissections

Case Reports in Genetics, Volume 2026, Issue 1, 2026.
Background MYH11 variants are associated with thoracic aortic aneurysms and dissections (TAADs) whether or not in combination with patent ductus arteriosus (PDA). MYH11 encodes vascular smooth muscle cell‐specific myosin heavy chain (MHC), and disruptions in this protein are thought to impair cellular function through disturbed intracellular force ...
Aria Atash, Heleen B. van der Zwaan, Maarten J. Cramer, Hans Kirkels, Pieter A. Doevendans, Barend M. E. Mees, Francesca Stillitano, Juliana F. Mazzeu   +7 more
wiley   +1 more source

Rare genetic variants within the 20 candidate genes in the aortopathy gene panel [13].

, 2018
Rare genetic variants within the 20 candidate genes in the aortopathy gene panel [13].
Martin Ungelenk (3385412), Tanja Zeller (112753), Ingo Kurth (499801), Evaldas Girdauskas (5570918), Niklas Neumann (5570921), Hermann Reichenspurner (123790), Johannes Petersen (4055716)   +6 more
core   +1 more source

289 Dilatative aortopathy in adults with repaired conotruncal defects [PDF]

, 2011
BackgroundDilatative aortopathy is a feature of tetralogy of Fallot (TOF). Structural abnormalities of the medial aorta have also been described for other conotruncal defects, like d-transposition of the great arteries (d-TGA).
Tobias Rutz, Andreas Wahl, Max Friedrich, Rutz, Tobias, Schwerzmann, Markus, Wahl, Andreas, Markus Schwerzmann, Friedrich, Max   +7 more
core   +1 more source

Aortopathy: Effects of Lipid-Lowering Therapy

Aortopathies can be congenital or acquired. Aortic atherosclerosis, abdominal aortic aneurysm, and degenerative aortic stenosis are some of the major manifestations of acquired aortopathy.
Sharma, Mala, Sharma, Tanya, Frishman, William H., Aronow, Wilbert S., Vollaro, Matthew   +4 more
core   +1 more source

Minimum Core Data Elements for Evaluation of Thoracic Aortic Disease

JACC: Advances
Thoracic aortic aneurysms predisposing to aortic dissections are rare but potentially deadly conditions that can be inherited in families. Understanding the natural history and genetic causes of thoracic aortic disease (TAD) requires international ...
Andreina Carbone, MD, Mary J. Roman, MD, Melissa L. Russo, MD, Kathryn W. Holmes, MD, MPH, Maya Brown-Zimmerman, MPH, CGC, John Elefteriades, MD, Catherine M. Otto, MD, Nicholas S. Burris, MD, Carlos Alberto Campello Jorge, MD, Scott C. DeRoo, MD, Maral Ouzounian, MD, PhD, Matthew D. Solomon, MD, PhD, Jay D. Humphrey, PhD, Bart Loeys, MD, PhD, Shaine A. Morris, MD, MPH, Guillaume Jondeau, MD, PhD, Scott A. LeMaire, MD, Sherene Shalhub, MD, MPH, Siddharth K. Prakash, MD, PhD   +18 more
doaj   +1 more source

Echocardiographic evidence of innate aortopathy in the human intracranial aneurysm. [PDF]

, 2014
BACKGROUND: Intracranial aneurysm (IA) is significantly more prevalent in patients with coarctation of the aorta or bicuspid aortic valve than in the general population, suggesting a common pathophysiology connecting IA and aortopathy.
Kon Chu, Jeong-Min Kim (168316), Jae-Kyu Roh, Sang Kun Lee, Kon Chu (168301), Jae-Kyu Roh (168360), Yong-Won Shin, Moon Hee Han (588595), Manho Kim, Moon Hee Han, Yong-Won Shin (588593), Young Dae Cho, Young Dae Cho (588594), Manho Kim (168349), Soon-Tae Lee, Soon-Tae Lee (168295), Keun-Hwa Jung, Jeong-Min Kim, Keun-Hwa Jung (168311), Sang Kun Lee (168354)   +19 more
core   +1 more source

Biomarkers of Collagen Metabolism in Hypertensive Aortopathy and Correlation with Strain in an African Cohort

Background Hypertensive aortopathy is associated with extracellular matrix remodelling and altered aortic mechanics, however the relationship between circulating biomarkers and deformation-based echocardiographic measures remains poorly characterised ...
Nishal A. Dullabh, Therese Dix-Peek, Ruchika Meel   +2 more
core   +1 more source

Association Between Bicuspid Aortic Valve Phenotype and Patterns of Valvular Dysfunction and Bicuspid Aortopathy Comprehensive Evaluation Using MDCT and Echocardiography [PDF]

, 2013
ObjectivesWe sought to define the clinical importance of an integrated classification of bicuspid aortic valve (BAV) phenotypes and aortopathy using multidetector computed tomography (MDCT).BackgroundAn association between BAV phenotypes and the pattern ...
Lim, Tae-Hwan, Kang, Duk-Hyun, Song, Jong-Min, Song, Jae-Kwan, Song, Hae Geun, Kim, Dae-Hee, Yang, Dong Hyun, Kang, Joon-Won, Baek, Seunghee   +8 more
core   +1 more source