Results 91 to 100 of about 4,070 (210)

Connective tissue disorder and high risk pregnancy: a case series with personalised external aortic root support (PEARS)

Nature Communications
Aortopathy including Marfan (MFS) and Loeys-Dietz syndrome (LDS) poses a high risk of aortic dissection, particularly during pregnancy and the puerperium.
Claudia Montanaro, Polona Kacar, Giulia Iannaccone, John Pepper, Gurleen Wander, Christoph A. Nienaber, Andreas Hoschtitzky, Mario Petrou, Hannah Douglas, Mark R. Johnson, Roshni R. Patel, Isma Rafiq, Michael A. Gatzoulis   +12 more
doaj   +1 more source

Identification and Verification of Differentially Methylated Regions in Cell-Free DNA as a Peripheral Biomarker for Bicuspid Aortic Valve Aortopathy

, 2020
Bicuspid aortic valve (BAV) is a common congenital cardiac malformation associated with aortopathy for which the progression of aortic dilation is difficult to predict at present. BAV aortopathy has been linked to genetic factors and abnormal hemodynamic
Maredia, Ashna Karimbhai
core   +1 more source

The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations

Methodist DeBakey Cardiovascular Journal
Thoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome.
Valeria E. Duarte, Jessica N. Richardson, Michael N. Singh   +2 more
doaj   +1 more source

Aortopathy and aortic valve surgery in patients with bicuspid aortic valve with and without raphe

Aim: To evaluate the association between raphe in bicuspid aortic valve (BAV) patients and valve dysfunction, aortopathy and aortic valve surgery in the REBECCA registry [REgistro della valvola aortica Bicuspide della Società Italiana di ECocardiografia
Carerj, Scipione, La Carrubba, Salvatore, Manuppelli, Vincenzo, Faden, Giacomo, Agostini, Francesco, Antonini-Canterin, Francesco, Bellino, Michele, Cresti, Alberto, Chirillo, Fabio, Nistri, Stefano, Colonna, Paolo, Dentamaro, Ilaria, Faggiano, Pompilio, Ciampi, Quirino, Galasso, Gennaro, Dasseni, Nicolò, Moreo, Antonella, Barbieri, Andrea, Faganello, Giorgio, Pepi, Mauro, Monte, Ines Paola, Giorgi, Mauro, Cameli, Matteo, Citro, Rodolfo, Cecconi, Moreno, Benedetto, Frank, Fabiani, Iacopo, Zito, Concetta, Bossone, Eduardo   +28 more
core   +1 more source

Genetics of bicuspid aortic valve aortopathy

, 2016
Purpose of review The incidence of aortic dilation and acute complications (rupture and dissection) is higher in patients with a bicuspid aortic valve (BAV), the most frequent congenital heart defect.
DELLA CORTE, Alessandro, Andreassi, Maria G   +1 more
core   +1 more source

Bicuspid aortic valve repair—current techniques, outcomes, challenges, and future perspectives

Frontiers in Cardiovascular Medicine
Bicuspid aortic valve (BAV) is a common congenital heart condition that can lead to some valve-related complications, such as aortic stenosis and/or regurgitation, and is often associated with aortic root dilation.
Haiyu Zhang, Haiyu Zhang
doaj   +1 more source

Sex Differences in Phenotypes of Bicuspid Aortic Valve and Aortopathy

, 2017
Background— This large multicenter, international bicuspid aortic valve (BAV) registry aimed to define the sex differences in prevalence, valve morphology, dysfunction (aortic stenosis/regurgitation), aortopathy, and ...
Enno T. van der Velde, Lawrence Ma, Ajmone Marsan, N., Louise McCormack, Ng, A.C.T., McCormack, L., Velde, E.T. van der, Parent, S., James W. Yip, Enache, R., Bogdan A. Popescu, Yip, J.W., Bart Mertens, Tiong Cheng Yeo, Ma, L., Vasileios Kamperidis, Delgado, V., Kian Keong Poh, Shanks, M., Nina Ajmone Marsan, Arnold C.T. Ng, Madelien V. Regeer, Yeo, T.C., Mertens, B., Bax, J.J., Sarah Parent, Poh, K.K., Regeer, M.V., Roxana Enache, Miriam Shanks, Jeroen J. Bax, Kamperidis, V., Kong, W.K.F., Victoria Delgado, Popescu, B.A., William K.F. Kong   +35 more
core   +1 more source

Differences between echocardiography and cardiac nuclear magnetic resonance parameters in children with bicuspid aortic valve-related aortopathy

Frontiers in Cardiovascular Medicine
ObjectivesThe bicuspid aortic valve (BAV) is the most common congenital heart defect. Patients with BAV frequently develop aortopathy, which depends on the dysfunction and morphotype of the BAV.AimThe aim of our study was to compare the echocardiography ...
Stasa Krasic, Stasa Krasic, Boris Zec, Vesna Topic, Sasa Popovic, Dejan Nesic, Marija Zdravkovic, Vladislav Vukomanovic, Vladislav Vukomanovic   +8 more
doaj   +1 more source

Human stem cell models for Marfan syndrome: a brief overview of the rising star in disease modelling

Frontiers in Cell and Developmental Biology
The introduction of pluripotent stem cells into the field of disease modelling resulted in numerous opportunities to study and uncover disease mechanisms in a petri dish.
Jeffrey Aalders, Laura Muiño Mosquera, Laura Muiño Mosquera, Jolanda van Hengel   +3 more
doaj   +1 more source

Role of a Transient Receptor Potential Channels in Marfan Syndrome-induced Aortopathy and Cardiomyopathy [PDF]

, 2016
Marfan syndrome (MFS) represents a genetic disorder with variable phenotypic expression. The main cardiovascular sequelae of MFS include aortic aneurysm/dissection and cardiomyopathy. While significant advances in the understanding of TGF-?
Westergaard, NM, Cavanaugh, Nicholas B., Qian, L, Turek, JW   +3 more
core   +1 more source