Results 61 to 70 of about 5,408 (223)

Imaging-Based Phenotyping in Bicuspid Aortic Valve and Associated Aortopathy: A Retrospective Single-Center Study

Medicina
Background and Objectives: Bicuspid aortic valve (BAV) is a common congenital cardiac abnormality frequently associated with aortopathy and progressive aortic dilatation.
Laurynas Šarkinas, Nomeda Rima Valevičienė, Sigita Glaveckaitė, Darius Palionis   +3 more
doaj   +1 more source

BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)

Российский кардиологический журнал, 2014
Aim. To study different ways of development and combinational abilities of pathological changes common for bicuspid aortic valvulopathy. Material and methods. Totally 207 patients included, who had during previous 5 years been operated for progression of
S. L. Dzemeshkevitch, V. A. Ivanov, E. R. Charchian, E. P. Evseev, Yu. V. Frolova, A. N. Lugovoy, S. V. Fedulova, V. V. Khovrin, A. A. Bukaeva, E. V. Zaklyazminskaya   +9 more
doaj   +1 more source

Prognosis of Unrepaired Ascending Aorta after the Surgical Replacement of Bicuspid Aortic Valves

Journal of Chest Surgery, 2023
Background: The surgical threshold for bicuspid aortic valve (BAV)-related aortopathy is a matter of debate due to its uncertain etiology and prognosis.
Hong Ju Shin, Wan Kee Kim, Dong Kyu Kim, Ho Jin Kim, Joon Bum Kim   +4 more
doaj   +1 more source

Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe mechanism underlying aortic dilatation is still unknown. Vascular dilatation is thought to be the result of progressive aortic media degeneration caused by defective vascular matrix hemostasis, including TGF-β1 dysregulation.
Mikita Karalko, Marek Pojar, Lenka Zaloudkova, Vaclav Stejskal, Salifu Timbilla, Pavla Brizova, Jan Vojacek   +6 more
doaj   +1 more source

Novel MYH11 Splice Site Variant Causing Exon Skipping in a Family With Thoracic Aortic Aneurysms and Dissections

Case Reports in Genetics, Volume 2026, Issue 1, 2026.
Background MYH11 variants are associated with thoracic aortic aneurysms and dissections (TAADs) whether or not in combination with patent ductus arteriosus (PDA). MYH11 encodes vascular smooth muscle cell‐specific myosin heavy chain (MHC), and disruptions in this protein are thought to impair cellular function through disturbed intracellular force ...
Aria Atash, Heleen B. van der Zwaan, Maarten J. Cramer, Hans Kirkels, Pieter A. Doevendans, Barend M. E. Mees, Francesca Stillitano, Juliana F. Mazzeu   +7 more
wiley   +1 more source

4D Flow Analysis of BAV-Related Fluid-Dynamic Alterations: Evidences of Wall Shear Stress Alterations in Absence of Clinically-Relevant Aortic Anatomical Remodeling

Frontiers in Physiology, 2017
Bicuspid aortic valve (BAV) is the most common congenital cardiac disease and is a foremost risk factor for aortopathies. Despite the genetic basis of BAV and of the associated aortopathies, BAV-related alterations in aortic fluid-dynamics, and ...
Filippo Piatti, Francesco Sturla, Malenka M. Bissell, Selene Pirola, Massimo Lombardi, Igor Nesteruk, Alessandro Della Corte, Alberto C. L. Redaelli, Emiliano Votta   +8 more
doaj   +1 more source

Válvula Aórtica Bicúspide en población pediátrica [PDF]

, 2017
La válvula aórtica bicúspide (VAB) es la cardiopatía congénita más frecuente. En muchas ocasiones esta patología es totalmente asintomática, pero se sabe que conlleva un no desdeñable número de complicaciones.
Blanco Fernández, Fabián
core  

Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]

, 2017
Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J, Chu, Mon-Li, Halabi, Carmen M, Lee, Vivian S, Lin, Michelle, Mecham, Robert P   +5 more
core   +3 more sources

Cardiovascular genetic counselor decision making about discussing life insurance with patients

Journal of Genetic Counseling, Volume 34, Issue 6, December 2025.
Abstract Genetic counselors (GCs) educate patients about the benefits, risks, and limitations of genetic testing. The regulatory environment governing the use of genetic data in life insurance is not uniform internationally or within the United States (US).
Sara Cherny, Sarah Jurgensmeyer Langas, Miguel Moran, Susan Christian, Gregory Webster   +4 more
wiley   +1 more source

Bicuspid Aortic Valve: Morphology, Clinic, Diagnosis, Complications

Рациональная фармакотерапия в кардиологии, 2021
Bicuspid aortic valve refers to common (0.5-2% of the population) congenital heart defects that are asymptomatic throughout life, with valve dysfunction and/or aortopathy (pathia- from Greek pathos disease), manifested by expansion, aneurysm or ...
Y. L. Trysvetava
doaj   +1 more source