Results 61 to 70 of about 69,987 (253)
Apathy in Alzheimer's disease: Contribution to a clinical view on progression of dementia
Dementia & NeuropsychologiaIn addition to cognitive impairment, apathy is increasingly recognized as an important neuropsychiatric syndrome in Alzheimer's disease (AD). Aims: To identify the relationship between dementia severity and apathy levels, and to discuss the association ...
Florindo Stella +5 more
doaj +1 more source
Toward a Behavioral Reserve Model in Amyotrophic Lateral Sclerosis
Annals of Neurology, EarlyView.Objective Behavioral impairment is common in amyotrophic lateral sclerosis (ALS) and strongly affects autonomy, caregiver burden, and outcomes, yet predictors of vulnerability remain unclear. We investigated whether premorbid regulatory traits and socio‐educational exposures are associated with behavioral phenotypes in ALS within a behavioral reserve ...
Francesca Palumbo +14 more
wiley +1 more source
Apathy following cerebrovascular lesions.
, 1993 Although apathy has been reported to constitute a frequent sequela of stroke lesions, there have been no prospective studies on the frequency and correlates of apathy after stroke lesions. In the present study, we examined the frequency and correlates of
J P Fedoroff +4 more
core +1 more source
Annals of Neurology, EarlyView.Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato +7 more
wiley +1 more source
A Case of a 40‐year‐old Female with Speech Disturbance
Annals of Clinical and Translational Neurology, EarlyView.
Victoria Lorah, Michael V. Robers
wiley +1 more source
Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients
Annals of Neurology, EarlyView.Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer +14 more
wiley +1 more source
Association between frailty and apathy in community-dwelling elderly adults
Shiyong laonian yixue[Objective] To explore the correlation between frailty and apathy in community-dwelling elderly adults. [Methods] A cross-sectional study was conducted from September to December 2024.
TAO Lu, XIA Zeyan
doaj +1 more source
Detecting Apathy in Individuals with Parkinson’s Disease: A Systematic Review
Journal of Parkinson’s Disease, 2019 Background: Individuals experiencing apathy in Parkinson’s disease (PD) have a lack of emotion and motivation. Apathy often overlaps with comorbidities such as depression, and is sometimes difficult to detect. Objective: To examine diagnostic accuracy of
Bria Mele +3 more
doaj +1 more source
Arthroscopic Suprapectoral Biceps Tenodesis Using a Standard Suture Anchor Is Safe and Effective
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To evaluate the safety and efficacy of an arthroscopic technique of suprapectoral biceps tenodesis using a standard absorbable double‐loaded suture anchor. Methods This retrospective study includes all patients who underwent arthroscopic biceps tenodesis by the senior author between December 2017 and June 2020. Biceps tenodesis was performed in
Xavier A. Duralde +2 more
wiley +1 more source
Brain mechanisms underlying apathy [PDF]
, 2018 The past few decades have seen growing interest in the neuropsychiatric syndrome of apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed behaviour.
Le Heron, Campbell J. +5 more
core +3 more sources