Results 81 to 90 of about 247,946 (201)

Psychiatric profile of motor subtypes of de novo drug-naïve Parkinson's disease patients [PDF]

, 2018
Background: Parkinson's disease (PD) is a heterogeneous neurodegenerative disorder. It is well established that different motor subtypes of PD evolve with different clinical courses and prognoses.
Assogna, F, Caltagirone, C, Cravello, L, Mercuri, B, Pellicano, C, Pierantozzi, M, Pontieri, Fe, Savini, C, Spalletta, G, Stefani, A   +9 more
core   +2 more sources

Improvement of apathy in early Parkinson’s disease

npj Parkinson's Disease
Apathy is a disabling symptom in Parkinson’s disease (PD). The effect of dopaminergic treatment on apathy is inconsistent, depending on the stage of the disease, the type of apathy and strongly influenced by placebo effect.
A. Castrioto, E. Schmitt, M. Anheim, S. Meoni, H. Klinger, D. Sourd, P. Pelissier, E. Lhommée, A. Bichon, C. Tranchant, E. Moro, V. Fraix, S. Thobois, P. Krack   +13 more
doaj   +1 more source

Apathy and Impulsivity Co‐Occur in Huntington's Disease

Brain and Behavior
Background Apathy is a debilitating behavioral change in Huntington's disease (HD), but impulsivity in HD has not been well documented, and the co‐occurrence of these behaviors in HD has not been investigated.
Lee‐Anne Morris, Kyla‐Louise Horne, Laura Paermentier, Christina M. Buchanan, Michael MacAskill, Daniel Myall, Masud Husain, Richard Roxburgh, Tim Anderson, Campbell Le Heron   +9 more
doaj   +1 more source

Apathy in Parkinson's disease patients

Неврология, нейропсихиатрия, психосоматика, 2014
pathy in Parkinson's disease (PD) patients is one of the least studied manifestations of a broad range of neuropsychic disorders. According to numerous researchers, the rate of apathy in PD patients is 17–80%.
M. R. Nodel
doaj   +1 more source

Prefrontal hyperactivation during dual-task walking related to apathy symptoms in older individuals

PLoS ONE, 2022
Increasing evidence associates apathy with worsening in cognitive performance and greater risk of dementia, in both clinical and healthy older populations.
Deborah Talamonti, Emma Gabrielle Dupuy, Sarah Boudaa, Thomas Vincent, Sarah Fraser, Anil Nigam, Frédéric Lesage, Sylvie Belleville, Christine Gagnon, Louis Bherer   +9 more
doaj  

Examining apathy prevalence and associated factors among older adults after the Great East Japan Earthquake: a mixed-methods study

BMC Geriatrics
Background Apathy is one of the psychological symptoms seen in post-disaster survivors. Apathy in older adults has been suggested to be associated with functional decline, but the actual situation and associated factors of apathy in the affected areas ...
Mari Yamashita, Satoshi Seino, Yu Nofuji, Yasuhiro Sugawara, Tsuyoshi Okamura, Kiyo Kawakubo, Shoji Shinkai, Yoshinori Fujiwara   +7 more
doaj   +1 more source

Facial Emotion Recognition Impairment in Patients with Parkinson's Disease and Isolated Apathy

Parkinson's Disease, 2010
Apathy is a frequent feature of Parkinson's disease (PD), usually related with executive dysfunction. However, in a subgroup of PD patients apathy may represent the only or predominant neuropsychiatric feature.
Mercè Martínez-Corral, Javier Pagonabarraga, Gisela Llebaria, Berta Pascual-Sedano, Carmen García-Sánchez, Alexandre Gironell, Jaime Kulisevsky   +6 more
doaj   +1 more source

Apathy in Older Adults With and Without Dementia: An Integrative Review of Barriers and Facilitators to Care

SAGE Open
Despite the detrimental impact of apathy on the cognition, functional abilities, and quality of life of older people, it is often under-rated and under-managed.
Aderonke Agboji, Shannon Freeman, Davina Banner, Annie Duchesne, Joshua Armstrong, Melinda Martin-Khan   +5 more
doaj   +1 more source

Dimensions of Apathy in Parkinson's Disease: Exploratory Factor Analysis of the Apathy Scale

Journal of Parkinson’s Disease, 2012
Apathy, an intrinsic disorder of motivation, can manifest in cognitive, affective, and behavioral domains. Recent attempts to formalize diagnostic criteria for apathy have advocated this triadic structure.
Daniel B. Kay, Lindsey Kirsch-Darrow, Laura B. Zahodne, Michael S. Okun, Dawn Bowers   +4 more
doaj   +1 more source

Apathy and affective symptoms associated with elevated plasma neurofilament light but not p‐tau181 in Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Apathy and affective neuropsychiatric symptoms (NPS) are prevalent in Alzheimer's disease (AD), yet their neurobiological cause is still unclear.
Matthew J. Y. Kang, Dhamidhu Eratne, Samantha M. Loi, Christa Dang, Alexander F. Santillo, Henrik Zetterberg, Kaj Blennow, Philip B. Mitchell, Malcolm Hopwood, Charles B. Malpas, Dennis Velakoulis   +10 more
doaj   +1 more source