Results 181 to 190 of about 12,228 (219)
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Peptides, 2022
The apelin/apelin receptor (ApelinR) signal transduction pathway exerts essential biological roles, particularly in the cardiovascular system. Disturbances in the apelin/ApelinR axis are linked to vascular, heart, kidney, and metabolic disorders. Therefore, the apelinergic system has surfaced as a critical therapeutic strategy for cardiovascular ...
Amanda Almeida de Oliveira +1 more
exaly +3 more sources
The apelin/apelin receptor (ApelinR) signal transduction pathway exerts essential biological roles, particularly in the cardiovascular system. Disturbances in the apelin/ApelinR axis are linked to vascular, heart, kidney, and metabolic disorders. Therefore, the apelinergic system has surfaced as a critical therapeutic strategy for cardiovascular ...
Amanda Almeida de Oliveira +1 more
exaly +3 more sources
Elabela/Toddler and apelin bind differently to the apelin receptor
The FASEB Journal, 2020Abstract Like apelin (pE13F, K17F), Elabela/Toddler is an endogenous ligand of the apelin receptor playing a key role in cardiovascular development. Elabela/Toddler exists as peptide fragments of 32 (Q32P), 22 (K22P) and 11 (C11P) amino acids.
Couvineau, Pierre +2 more
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Clinica Chimica Acta, 2018
Apelin, a regulatory peptide, is a ligand of the APJ receptor that belongs to the G protein-coupled receptor family. Apelin and APJ are widely distributed in the body and play potential physiological roles in the cytoprotection of many internal organs.
Hanna Antushevich, Maciej Wójcik
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Apelin, a regulatory peptide, is a ligand of the APJ receptor that belongs to the G protein-coupled receptor family. Apelin and APJ are widely distributed in the body and play potential physiological roles in the cytoprotection of many internal organs.
Hanna Antushevich, Maciej Wójcik
openaire +2 more sources
Effects of apelin levels, apelin gene polymorphism and apelin receptor
2017Abstract Not ...
Keleş, Dilek +3 more
openaire +1 more source
Neuroprotective effect of apelin-13 and other apelin forms—a review
Pharmacological ReportsNeurodegenerative diseases, which occur when neurons begin to deteriorate, affect millions of people worldwide. These age-related disorders are becoming more common partly because the elderly population has increased in recent years. While no treatments are accessible, every year an increasing number of therapeutic and supportive options become ...
Katarzyna Kamińska +3 more
openaire +2 more sources
2016
Over the past decades, obesity became a tremendous socioecological problem, reaching epidemic dimensions and the number of accompanying comorbidities including type 2 diabetes and cardiovascular diseases can be extended by different types of cancer.
Stefanie Kälin, Roland E. Kälin
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Over the past decades, obesity became a tremendous socioecological problem, reaching epidemic dimensions and the number of accompanying comorbidities including type 2 diabetes and cardiovascular diseases can be extended by different types of cancer.
Stefanie Kälin, Roland E. Kälin
openaire +1 more source
Hyperandrogenemia elevates expression of apelin and apelin receptor protein in the mice pituitary
Journal of Experimental Zoology Part A: Ecological and Integrative PhysiologyAbstractHyperandrogenemia is associated with polycystic ovarian syndrome (PCOS) and imbalances in the pituitary hormones, luteinizing hormone (LH) and follicle‐stimulating hormone (FSH) levels. Apelin and its receptor, APJ (class A, rhodopsin‐like G‐ protein‐coupled receptor), belongs to adipokines, and its expression has been shown in the pituitary ...
Preethi Riba +4 more
openaire +2 more sources