Results 121 to 130 of about 25,813 (258)

Guidelines on the Use of Therapeutic Apheresis in Clinical PracticeEvidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Sixth Special Issue

, 2013
The American Society for Apheresis (ASFA) JCA Special Issue Writing Committee is charged with reviewing, updating and categorizating indications for therapeutic apheresis.
Williams, Mark E., Wu, Yanyun, Winters, Jeffrey L., Delaney, Meghan, Shaz, Beth H., Schwartz, Joseph, Padmanabhan, Anand, Szczepiorkowski, Zbigniew M., Linenberger, Michael L., Balogun, Rasheed A.   +9 more
core   +1 more source

Advances in the treatment of systemic lupus erythematosus: Biologicals, small‐molecular agents, and cell‐depleting therapies coming to the clinic

Journal of Internal Medicine, Volume 300, Issue 4, Page 461-479, October 2026.
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, Volume 159, Issue 6, Page 1521-1534, 15 September 2026.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Current advances in 2025: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee

Transfusion, EarlyView.
Nabiha H. Saifee, Jennifer Andrews, Mary Berg, Stella T. Chou, Mischa Covington, Elizabeth P. Crowe, Ruchika Goel, Juliana A. Guarente, Tina Ipe, Jeremy W. Jacobs, Jessica Jacobson, Cyril Jacquot, Jenna Khan, Thane A. Kubik, Theodros Mamo, Michael F. Murphy, Kerry O'Brien, Monica B. Pagano, Anil K. Panigrahi, Jacqueline N. Poston, Scott E. Potter, Simon J. Stanworth, Moritz Stolla, Alyssa Ziman, Ryan A. Metcalf   +24 more
wiley   +1 more source

Mitochondrial DNA mutations are associated with impaired oxidative phosphorylation and enhanced imatinib response in chronic myeloid leukemia

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Mitochondrial DNA (mtDNA) mutations are frequently observed in cancer, but their clinical and functional significance in chronic myeloid leukemia (CML) remains incompletely defined. Here, we show that a distinct mtDNA mutational landscape is associated with mitochondrial metabolic programs and response to imatinib therapy in CML.
Ilaria S. Pagani, Vaidehi Krishnan, John F. Ouyang, Chung H. Kok, BeiJun Chen, Kian Leong Lee, Cong M. Pham, Paul Wang, Elyse Page, Phuong Dang, Verity A. Saunders, Jane James, Kelly Lim, Stefano Mangiola, Yingnan Gao, Naranie Shanmuganathan, Agnes Yong, Susan Branford, Charles Chuah, David T. Yeung, Deborah L. White, Vignir G. Helgason, Daniel Thomas, S. Tiong Ong, Timothy P. Hughes, David M. Ross   +25 more
wiley   +1 more source

A case report of the cascade filtration system: A safe and effective method for low-density lipoprotein apheresis during pregnancy

, 2008
PubMedID: 18937724Women with familial hypercholesterolemia (FH) should be treated effectively during pregnancy, as elevated low-density lipoprotein cholesterol (LDL-C) levels may result in life-threatening consequences.
Haydardedeoglu B., Guvenc B., Tekinturhan F., Ertorer M.E.   +3 more
core   +1 more source

Targeted proteomics reveal histiocytosis‐associated neurodegeneration signatures

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), yet its underlying biology and reliable biomarkers remain poorly defined. The aim of this study was to (1) gain insight into neuroimmunological mechanisms governing ND and (2) assess the clinical value of established and novel biomarkers for ND‐LCH.
Egle Kvedaraite, Magda Lourda, Johannes Bastiaan Munting, Matthias Papo, Martin Jädersten, Yoko Shioda, Kenichi Sakamoto, Daniel Martín Muñoz, Panagiotis Andriopoulos, Francesco Pegoraro, Evaldas Laurencikas, Ingrid Kühnle, Joakim Wille, Leonie Naeije, Helena Olkinuora, Indranil Sinha, Daniel W. Hagey, Selma Olsson‐Åkefeldt, Fleur Cohen‐Aubart, Gustaf Österlundh, Mattias Svensson, Ahmed Idbaih, Fredrik Piehl, Kaj Blennow, Henrik Zetterberg, Tatiana Greenwood von Bahr, Désirée Gavhed, Akira Morimoto, Julien Haroche, Jan‐Inge Henter   +29 more
wiley   +1 more source

The Italian Registry of Pediatric Therapeutic Apheresis: a concise report on the 2005 activity

, 2008
The results of the 2005 Survey of the Italian Society for Apheresis and Cell Manipulation (SIdEM) reporting on the pediatric procedures carried out in 18 Italian Apheresis Units are presented here.
TISON T, VICARIOTO M, STEFANUTTI, Claudia, BAGATELLA P, DE SILVESTRO G, MARSON P.   +5 more
core   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source