Results 131 to 140 of about 25,813 (258)

Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators

open access: yesFrontiers in Immunology
BackgroundHigh-dose glucocorticoids are the standard treatment for acute relapses in patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).
Michael Hecker   +21 more
doaj   +1 more source

Therapeutic apheresis in autoimmune diseases

open access: yes, 2013
Rolf Bambauer,1 Reinhard Latza,2 Carolin Bambauer,3 Daniel Burgard,4 Ralf Schiel5 1Institute for Blood Purification, Homburg, 2Laboratorium of Medicine, St Ingbert, 3Main Hospital Darmstadt, Darmstadt, 4Herz Zentrum, Cardiology, Völklingen ...
Bambauer R   +4 more
core  

Apheresis practice variation during the COVID-19 pandemic: Results of a survey

open access: yes
Background: The COVID-19 pandemic affected healthcare delivery across all specialties including apheresis. To describe the changes in apheresis service practices that occurred during the pandemic, the American Society for Apheresis (ASFA) Apheresis ...
Tanhehco, Yvette C   +12 more
core   +1 more source

Hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease: A real‐world study in Quebec

open access: yesBritish Journal of Haematology, Volume 209, Issue 3, Page 1291-1300, September 2026.
Summary Haemoglobin SC (HbSC) disease is the second most prevalent form of sickle cell disease, but evidence for hydroxyurea (hydroxycarbamide; HU) to prevent pain episodes was limited until the prospective identification of variables as outcomes for treatment (PIVOT) trial.
Alice Girard   +10 more
wiley   +1 more source

Comparative effectiveness of chimeric antigen receptor (CAR) T‐cell therapy versus historical controls in patients with relapse/refractory aggressive B‐cell lymphoma: An indirect treatment comparison in the real‐world setting

open access: yesBritish Journal of Haematology, Volume 209, Issue 3, Page 1230-1238, September 2026.
Summary Single‐arm studies demonstrate dramatic improvements in survival in patients with relapsed/refractory (R/R) aggressive B‐cell lymphomas but with significant toxicities and at exceptionally high costs. The objective of this study was to evaluate the real‐world health outcomes of aggressive B‐cell lymphoma patients treated with publicly funded ...
Pierre J. A. Villeneuve   +17 more
wiley   +1 more source

Immune features of graft‐derived mucosal‐associated invariant T cells predict gastrointestinal graft‐versus‐host disease

open access: yesBritish Journal of Haematology, Volume 209, Issue 3, Page 1208-1219, September 2026.
Summary Gastrointestinal acute graft‐versus‐host disease (GI aGVHD) remains a major complication after allogeneic haematopoietic stem cell transplantation (allo‐HSCT), and early risk identification and intervention are essential for improving outcomes.
Gao Mengge   +8 more
wiley   +1 more source

Practical Guidance on Initiating and Switching Targeted Immunotherapies in Generalised Myasthenia Gravis: A German–Austrian Expert Opinion Paper

open access: yesEuropean Journal of Neurology, Volume 33, Issue 9, September 2026.
ABSTRACT Background The therapeutic landscape of generalised myasthenia gravis (gMG) has evolved substantially with the approval of targeted immunotherapies, including complement C5 inhibitors (C5‐I) and neonatal Fc receptor inhibitors (FcRn‐I). While pivotal trials have demonstrated marked efficacy in defined subgroups, real‐world experience reveals ...
Andreas Meisel   +17 more
wiley   +1 more source

Impact of delayed blood donation sample processing and testing on SARS‐CoV‐2 serological assay results in an evolving pandemic response

open access: yesTransfusion, Volume 66, Issue 9, Page 1800-1810, September 2026.
Abstract Background The two largest US blood collection organizations led a multiphased, multicenter nationwide SARS‐CoV‐2 blood donor‐based serosurveillance program. The potential impact of delayed sample processing and prolonged refrigerated or frozen storage on anti‐SARS‐CoV‐2 antibody detection was investigated.
Marion C. Lanteri   +15 more
wiley   +1 more source

Usefulness of pegfilgrastim for allogeneic peripheral blood stem cell collection from healthy donors

open access: yesTransfusion, Volume 66, Issue 9, Page 1811-1818, September 2026.
Abstract Background Granulocyte colony‐stimulating factor (G‐CSF)‐based mobilization is essential for peripheral blood stem cell (PBSC) collection for allogeneic transplantation. Conventional daily G‐CSF requires repeated dosing and dose adjustment and often necessitates leukapheresis over multiple consecutive days, increasing donor burden. Single‐dose
Tomoshige Shimizu   +11 more
wiley   +1 more source

Comparison of four different in vitro assays for prediction of potential RBC antibody clinical significance

open access: yesTransfusion, Volume 66, Issue 9, Page 1830-1839, September 2026.
Abstract Background The monocyte monolayer assay (MMA) uses monocytes, but it is known that antibody‐mediated hemolysis occurs in macrophages. Whether the use of macrophages would improve the predictive capacity of the MMA is unclear. Also, it is unclear if RBC alloantibodies contribute to hemolysis via antibody‐dependent cellular cytotoxicity (ADCC ...
Yeniley Ruiz Noa   +6 more
wiley   +1 more source

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