Equine rhinitis A virus and its low pH empty particle: clues towards an aphthovirus entry mechanism?
PLoS Pathogens, 2009 Equine rhinitis A virus (ERAV) is closely related to foot-and-mouth disease virus (FMDV), belonging to the genus Aphthovirus of the Picornaviridae. How picornaviruses introduce their RNA genome into the cytoplasm of the host cell to initiate replication ...
Tobias J Tuthill +7 more
doaj +5 more sources
Development of a Conventional Reverse Transcription‐PCR System for Broad Detection of Bovine Rhinitis A Virus [PDF]
Veterinary Medicine and ScienceBovine rhinitis A virus (BRAV) is a virus of the genus Aphthovirus, family Picornaviridae. BRAV has recently attracted interest as a causative agent in bovine respiratory disease complex (BRDC).
Shunjiro Koizumi +3 more
doaj +3 more sources
Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes. [PDF]
PLoS Pathogens, 2017 Picornaviruses are non-enveloped RNA viruses that enter cells via receptor-mediated endocytosis. Because they lack an envelope, picornaviruses face the challenge of delivering their RNA genomes across the membrane of the endocytic vesicle into the ...
Elisabetta Groppelli +9 more
doaj +4 more sources
Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids [PDF]
VirusesA diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia.
Andrew Noel +6 more
doaj +2 more sources
Foot-and-mouth disease virus 3C protease as virulence determinant plays multiple roles in cleaving viral polyprotein and host factors [PDF]
VirulenceFoot-and-mouth disease virus (FMDV) can cause a severe infectious disease that primarily affects even-toed ungulates. FMDV is classified into the genus of Aphthovirus in the family Picornaviridae.
Houcheng Zhou +6 more
doaj +2 more sources
Molecular characterization of VP1 gene during the foot and mouth disease virus outbreak in East Java, Indonesia, in 2022 [PDF]
Veterinary WorldBackground and Aim: Foot and mouth disease (FMD) is highly contagious in cloven-hoofed animals, and it causes outbreaks in Indonesia and several countries worldwide.
Zayyin Dinana +11 more
doaj +2 more sources
Heat shock protein 90 chaperone activity is required for hepatitis A virus replication [PDF]
Journal of VirologyHSP90 heat shock chaperones are essential for maintaining cellular proteostasis, as well as the ATP-dependent folding and functional maturation of many viral proteins. As a result, inhibitors of HSP90 have broad antiviral activity, disrupting replication
You Li +13 more
doaj +2 more sources
Cryo-EM structure of the Seneca Valley virus A-particle and related structural states [PDF]
Journal of VirologyPicornavirus cell entry requires a series of capsid protein conformational changes leading to genome uncoating. For enteroviruses, receptor binding triggers the transition from a full (F) capsid to an altered (A) particle before releasing its genome and ...
Rosheny Kumaran +7 more
doaj +2 more sources
Foot-and-Mouth Disease Virus Interserotypic Recombination in Superinfected Carrier Cattle
Pathogens, 2022 Viral recombination contributes to the emergence of novel strains with the potential for altered host range, transmissibility, virulence, and immune evasion.
Ian Fish +10 more
doaj +1 more source
Recovery of viral RNA and infectious foot-and-mouth disease virus from positive lateral-flow devices [PDF]
, 2014 Foot-and-mouth disease Virus (FMDV) is an economically important, highly contagious picornavirus that affects both wild and domesticated cloven hooved animals. In developing countries, the effective laboratory diagnosis of foot-and-mouth disease (FMD) is
Armson, Bryony +10 more
core +10 more sources