Equine rhinitis A virus and its low pH empty particle: clues towards an aphthovirus entry mechanism?
Equine rhinitis A virus (ERAV) is closely related to foot-and-mouth disease virus (FMDV), belonging to the genus Aphthovirus of the Picornaviridae. How picornaviruses introduce their RNA genome into the cytoplasm of the host cell to initiate replication ...
Tobias J Tuthill +7 more
doaj +3 more sources
Development of a Conventional Reverse Transcription‐PCR System for Broad Detection of Bovine Rhinitis A Virus [PDF]
Bovine rhinitis A virus (BRAV) is a virus of the genus Aphthovirus, family Picornaviridae. BRAV has recently attracted interest as a causative agent in bovine respiratory disease complex (BRDC).
Shunjiro Koizumi +3 more
doaj +3 more sources
Diagnosis of persistent aphthovirus infection and its differentiation from vaccination response in cattle by use of enzyme-linked immunoelectrotransfer blot analysis with bioengineered nonstructural viral antigens [PDF]
A highly sensitive enzyme-linked immunoelectrotransfer blot (EITB) assay, capable of detecting aphthovirus-specific antibodies to replicating virus in sera from cattle with persistent infection, was developed. The assay uses a set of purified recombinant
Ingrid E. Bergmann +4 more
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Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids [PDF]
A diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia.
Andrew Noel +6 more
doaj +2 more sources
This datasheet on Aphthovirus covers Identity, Distribution, Hosts/Species Affected.
Marvin J. Grubman, Teresa de los Santos
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Molecular characterization of VP1 gene during the foot and mouth disease virus outbreak in East Java, Indonesia, in 2022 [PDF]
Background and Aim: Foot and mouth disease (FMD) is highly contagious in cloven-hoofed animals, and it causes outbreaks in Indonesia and several countries worldwide.
Zayyin Dinana +11 more
doaj +2 more sources
Heat shock protein 90 chaperone activity is required for hepatitis A virus replication [PDF]
HSP90 heat shock chaperones are essential for maintaining cellular proteostasis, as well as the ATP-dependent folding and functional maturation of many viral proteins. As a result, inhibitors of HSP90 have broad antiviral activity, disrupting replication
You Li +13 more
doaj +2 more sources
Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation [PDF]
Sonia López de Quinto +1 more
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Cryo-EM structure of the Seneca Valley virus A-particle and related structural states [PDF]
Picornavirus cell entry requires a series of capsid protein conformational changes leading to genome uncoating. For enteroviruses, receptor binding triggers the transition from a full (F) capsid to an altered (A) particle before releasing its genome and ...
Rosheny Kumaran +7 more
doaj +2 more sources
Guanidine-resistant mutants of aphthovirus induce the synthesis of an altered nonstructural polypeptide, P34 [PDF]
Keith Saunders, Andrew M. Q. King
openalex +2 more sources

