Results 91 to 100 of about 4,215 (205)

RNA‐Seq analysis reveals the different mechanisms triggered by bovine and equine after infection with FMDV

Veterinary Medicine and Science, Volume 10, Issue 5, September 2024.
Both nonsusceptible animals (horses) and susceptible animals (cows) have integrin receptors in their nasopharyngeal tissues that can help FMDV enter cells. Infection with the FMDV promotes apoptosis in cows, while the opposite is true for horses. Autophagy‐related genes show a significant increase in expression in horses infected with FMDV.
Yi Wu, Lu Li, Wanfu Bai, Tao Li, Xiaoying Qian, Yiyi Liu, Shenyuan Wang, Chunxia Liu, Fang Wan, Dong Zhang, Yingchun Liu, Kaifeng Wu, Yu Ling, Huanmin Zhou, Fanhua Meng, Yanru Zhang, Junwei Cao   +16 more
wiley   +1 more source

Application of the Ceditest FMDV type O and FMDV-NS enzyme-linked immunosorbent assays for detection of antibodies against Foot-and-mouth disease virus in selected livestock and wildlife species in Uganda [PDF]

, 2012
Diagnosis and control of Foot-and-mouth disease virus (FMDV) requires rapid and sensitive diagnostic tests. Two antibody enzyme-linked immunosorbent assay (ELISA) kits, Ceditest® FMDV-NS for the detection of antibodies against the nonstructural ...
Alexandersen S, Ayebazibwe C, Cartwright B, Cunliffe HR, Dellers RW, Mwiine FN, Thomson GR   +6 more
core   +1 more source

The dual role of a highly structured RNA (the S fragment) in the replication of foot‐and‐mouth disease virus

The FASEB Journal, Volume 38, Issue 14, 31 July 2024.
RNA structures are essential for genome replication of single stranded positive sense RNA viruses. Here, we confirm the conserved structure of the foot‐and‐mouth disease virus (FMDV) short (S) fragment, a c. 360 nucleotide‐long stem‐loop in the 5′ UTR of the viral genome, by SHAPE and comparative bioinformatic approaches.
Joseph C. Ward, Lidia Lasecka‐Dykes, Samuel J. Dobson, Sarah Gold, Natalie J. Kingston, Morgan R. Herod, Donald P. King, Tobias J. Tuthill, David J. Rowlands, Nicola J. Stonehouse   +9 more
wiley   +1 more source

Challenges of Controlling Foot‐and‐Mouth Disease in Pastoral Settings in Africa

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
Foot‐and‐mouth disease (FMD) is a highly devastating viral disease affecting all cloven‐hoofed animals. The disease threatens food security and livelihoods across different parts of the world. FMD is endemic in Africa; where the continuous circulation of the disease impacts the livelihoods of pastoral communities by reducing the quality and quantity of
Mkama M. Mashinagu, Philemon N. Wambura, Donald P. King, David J. Paton, Francois Maree, Sharadhuli I. Kimera, Mark M. Rweyemamu, Christopher J. Kasanga, Subodh Samrat   +8 more
wiley   +1 more source

[Synthesis of 10S particles in cells infected with aphthovirus].

Revista Argentina de microbiologia, 1989
In the present study, evidence is presented for the existence of a morphogenetic intermediary that may be a precursor of the procapsids in the assembling process. BHK21 clone 13S cells were infected with Aphthovirus A24 (Cruzeiro strain), and pulse-chase experiments were carried out using 3H-leucine.
A, Gómez Yafal, P, Polacino, G, Kaplan, E L, Palma   +3 more
openaire   +1 more source

Analysis of Coinfection Pathogens From Foot‐and‐Mouth Disease Virus Persistently Infected Cattle Using Oxford Nanopore Sequencing

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
The persistent infection caused by foot‐and‐mouth disease virus (FMDV) still lacks a reliable explanation, as its etiology and maintenance are intricate and potentially involve concurrent infections with multiple pathogens. In this study, we utilized the nanopore platform for direct sequencing of clinical samples obtained from cattle persistently ...
Shuang Wang, Sumin Wei, Yaozhong Ding, Yun Zhang, Zhihui Zhang, Shiqi Sun, Huichen Guo, Shuanghui Yin, Chunfu Zheng   +8 more
wiley   +1 more source

Foot and Mouth Disease Vaccine Development and Challenges in Inducing Long-Lasting Immunity: Trends and Current Perspectives

Veterinary Medicine: Research and Reports, 2021
Ambaye Kenubih University of Gondar, College of Veterinary Medicine and Animal Sciences, Para-Clinical Studies, Gondar, EthiopiaCorrespondence: Ambaye Kenubih Email ambayken@yahoo.comAbstract: Foot and mouth disease (FMD) is an extremely contagious viral
Kenubih A
doaj  

Pandemic Strain of Foot-and-Mouth Disease Virus Serotype O

Emerging Infectious Diseases, 2005
A particular genetic lineage of foot-and-mouth disease virus (FMDV) serotype O, which we have named the PanAsia strain, was responsible for an explosive pandemic in Asia and extended to parts of Africa and Europe from 1998 to 2001. In 2000 and 2001, this
Nick J. Knowles, Alan R. Samuel, Paul R. Davies, Rebecca J. Midgley, Jean-François Valarcher   +4 more
doaj   +1 more source

Processing of the VP1/2A Junction Is Not Necessary for Production of Foot-and-Mouth Disease Virus Empty Capsids and Infectious Viruses: Characterization of “Self-Tagged” Particles [PDF]

, 2013
The foot-and-mouth disease virus (FMDV) capsid protein precursor, P1-2A, is cleaved by 3C(pro) to generate VP0, VP3, VP1, and the peptide 2A. The capsid proteins self-assemble into empty capsid particles or viruses which do not contain 2A.
A. Botner, Acharya, Bablanian, Baranowski, Belsham, Belsham, Belsham, Berryman, Birtley, Borovec, Bøtner, C. Polacek, Carrillo, Cohen, Curry, Curry, Donnelly, Donnelly, Ellard, Ferris, Fry, Fuerst, G. J. Belsham, Goodwin, Grubman, Grubman, Guarne, Gullberg, Hinton, Johns, Lawrence, Logan, M. Gullberg, Maree, Martin, Martin-Acebes, Nayak, O'Donnell, O'Donnell, Petersen, Polacek, Porta, Probst, Rachow, Reed, Roeder, Ryan, Sambrook, Seago, Strebel, Toyoda, Wang, Yu, Zhao, Zunszain   +54 more
core   +1 more source

Genetic diversity of serotype A foot-and-mouth disease viruses in Kenya from 1964 to 2013; implications for control strategies in eastern Africa [PDF]

, 2014
Serotype A is the most genetically and antigenically diverse of the foot-and-mouth disease virus (FMDV) serotypes. Records of its occurrence in Kenya date back to 1952 and the antigenic diversity of the outbreak viruses in this region is reflected by the
Balinda, Sheila N., Belsham, Graham J., Heller, Rasmus, Masembe, Charles, Muwanika, Vincent B., Sangula, Abraham K., Siegismund, Hans R., Wekesa, Sabenzia N.   +7 more
core   +1 more source