The FASEB Journal, Volume 38, Issue 14, 31 July 2024.RNA structures are essential for genome replication of single stranded positive sense RNA viruses. Here, we confirm the conserved structure of the foot‐and‐mouth disease virus (FMDV) short (S) fragment, a c. 360 nucleotide‐long stem‐loop in the 5′ UTR of the viral genome, by SHAPE and comparative bioinformatic approaches.
Joseph C. Ward +9 more
wiley +1 more source
Molecular Characterization of the Viroporin Function of Foot-and-Mouth Disease Virus Nonstructural Protein 2B [PDF]
, 2018 Nonstructural protein 2B of foot-and-mouth disease (FMD) virus (FMDV) is comprised of a small, hydrophobic, 154-amino-acid protein. Structure-function analyses demonstrated that FMDV 2B is an ion channel-forming protein.
Aguilella, Vicente +13 more
core +1 more source
The potential consequences for cell Signaling by a class of NOD-Like Receptor proteins (NLRs) bearing an N-terminal signal sequence [PDF]
, 2017 The authors gratefully acknowledge the support of the UK Biotechnology and Biological Sciences Research Council (BBSRC) for the work on cellular 2A-like sequences.Publisher PDFPeer ...
de Felipe, Pablo +5 more
core
Rapid production of a chimeric antibody-antigen fusion protein based on 2A-peptide cleavage and green fluorescent protein expression in CHO cells [PDF]
, 2019 To enable large-scale antibody production, the creation of a stable, high producer cell line is essential. This process often takes longer than 6 months using standard limited dilution techniques and is very labor intensive.
Cox, Eric +2 more
core +2 more sources
In planta production of two peptides of the Classical Swine Fever Virus (CSFV) E2 glycoprotein fused to the coat protein of potato virus X [PDF]
, 2006 Background Classical Swine Fever (CSFV) is one of the most important viral infectious diseases affecting wild boars and domestic pigs. The etiological agent of the disease is the CSF virus, a single stranded RNA virus belonging to the family ...
Marconi, Gianpiero +8 more
core +1 more source
Virology, 1996 During serial undiluted passage of a clonal population of foot-and-mouth disease virus (FMDV C-S8c1) in BHK-21 cells, two species of defective RNA were generated and selected. Sequence analysis revealed that they included deletions within the L-coding region, and retained the correct reading frame for viral protein synthesis.
Charpentier, N. +3 more
openaire +3 more sources
Frontiers in Veterinary Science, 2018 Foot-and-mouth disease (FMD), caused by FMD virus (FMDV; Aphthovirus, Picornaviridae), is a highly contagious and economically important disease of cloven-hoofed domestic livestock and wildlife species worldwide.
Miranda R. Bertram +20 more
doaj +1 more source
Influence of brain-derived neurotrophic factor on pathfinding of dentate granule cell axons, the hippocampal mossy fibers [PDF]
, 2009 Mossy fibers, the dentate granule cell axons, are generated throughout an animal's lifetime. Mossy fiber paths and synapses are primarily restricted to the stratum lucidum within the CA3 region.
Makoto Tamura +6 more
core +2 more sources
Laboratory capacity for diagnosis of foot-and-mouth disease in Eastern Africa: implications for the progressive control pathway [PDF]
, 2013 Background Accurate diagnosis is pertinent to any disease control programme. If Eastern Africa is to work towards control of foot-and-mouth disease (FMD) using the Progressive Control Pathway for FMD (PCP-FMD) as a tool, then the capacity of national ...
Ayebazibwe, Chrisostom +6 more
core +4 more sources
Foot-and-mouth disease virus genome replication is unaffected by inhibition of type III phosphatidylinositol-4-kinases [PDF]
, 2016 Foot-and-mouth disease virus (FMDV) causes economically-damaging infections of cloven-hooved animals, with outbreaks resulting in large financial losses to the agricultural industry.
Belsham +9 more
core +1 more source