Results 11 to 20 of about 89 (67)
Abstract Rapid and accurate detection and serotyping of foot‐and‐mouth disease (FMD) virus (FMDV) is essential for implementing control policies against emergent FMD outbreaks. Current serotyping assays, such as VP1 reverse transcription‐polymerase chain reaction (RT‐PCR)/sequencing (VP1 RT‐PCR/sequencing) and antigen detection enzyme‐linked ...
Da‐Rae Lim+10 more
wiley +1 more source
Abstract The O/ME‐SA/Ind‐2001d has been the main foot‐and‐mouth disease virus (FMDV) lineage responsible for FMD epidemics outside the Indian subcontinent from 2013 to 2017. In 2014, outbreaks caused by this FMDV lineage were reported in Maghreb, where it was initially detected in Algeria and Tunisia and later in Morocco.
G. Pezzoni+11 more
wiley +1 more source
Picornavirus translation strategies
Upon the entry of the viral RNA into susceptible cells, cis‐ and trans‐regulatory elements coordinately determine picornavirus protein synthesis. Early in the infection, the cap‐dependent translation of host mRNAs is shut down, while viral RNA takes advantage of the IRES element, resulting in efficient synthesis of viral proteins.
Rosario Francisco‐Velilla+3 more
wiley +1 more source
Information on the circulation of foot‐and‐mouth disease (FMD) in Western Syria is very limited. It is known that the country is affected by a prolonged humanitarian crisis that may certainly have contributed to such lack of information and the latest available data date back to 2002.
Tiziana Trogu+15 more
wiley +1 more source
Foot‐and‐mouth disease (FMD) is a highly contagious viral disease of cloven‐footed livestock caused by foot‐and‐mouth disease virus (FMDV). FMD has significant impacts on farmers and national economies. The evolution and mutation of FMDV have contributed to the emergence of new strains of FMDV. Sequences of VP1 from 11 FMDV isolates in the Mekong Delta
Nguyen Phuc Khanh+5 more
wiley +1 more source
Both nonsusceptible animals (horses) and susceptible animals (cows) have integrin receptors in their nasopharyngeal tissues that can help FMDV enter cells. Infection with the FMDV promotes apoptosis in cows, while the opposite is true for horses. Autophagy‐related genes show a significant increase in expression in horses infected with FMDV.
Yi Wu+16 more
wiley +1 more source
RNA structures are essential for genome replication of single stranded positive sense RNA viruses. Here, we confirm the conserved structure of the foot‐and‐mouth disease virus (FMDV) short (S) fragment, a c. 360 nucleotide‐long stem‐loop in the 5′ UTR of the viral genome, by SHAPE and comparative bioinformatic approaches.
Joseph C. Ward+9 more
wiley +1 more source
Challenges of Controlling Foot‐and‐Mouth Disease in Pastoral Settings in Africa
Foot‐and‐mouth disease (FMD) is a highly devastating viral disease affecting all cloven‐hoofed animals. The disease threatens food security and livelihoods across different parts of the world. FMD is endemic in Africa; where the continuous circulation of the disease impacts the livelihoods of pastoral communities by reducing the quality and quantity of
Mkama M. Mashinagu+8 more
wiley +1 more source
The persistent infection caused by foot‐and‐mouth disease virus (FMDV) still lacks a reliable explanation, as its etiology and maintenance are intricate and potentially involve concurrent infections with multiple pathogens. In this study, we utilized the nanopore platform for direct sequencing of clinical samples obtained from cattle persistently ...
Shuang Wang+8 more
wiley +1 more source
Conservation of the secondary structure elements of the 5' untranslated region of cardio- and aphthovirus RNAs [PDF]
Evgeny V. Pilipenko+4 more
openalex +1 more source