Results 41 to 50 of about 4,184 (207)

Long-Term, Large-Population Passage of Aphthovirus Can Generate and Amplify Defective Noninterfering Particles Deleted in the Leader Protease Gene

Virology, 1996
During serial undiluted passage of a clonal population of foot-and-mouth disease virus (FMDV C-S8c1) in BHK-21 cells, two species of defective RNA were generated and selected. Sequence analysis revealed that they included deletions within the L-coding region, and retained the correct reading frame for viral protein synthesis.
N. Charpentier, Mercedes Dávila, Esteban Domingo, Cristina Escarmı́s   +3 more
openalex   +4 more sources

Effect of Expression of the Aphthovirus Protease 3C on Viral Infection and Gene Expression

Virology, 1995
Cells transformed with specific regions of the foot-and-mouth disease virus (FMDV) genome have been constructed and analyzed with respect to viability and susceptibility to FMDV infection. Constitutive expression of an active protease 3C under the control of the tk promoter has been documented by the ability of transformed cells to catalyze the ...
Encarnación Martı́nez-Salas, Esteban Domingo   +1 more
openalex   +3 more sources

Virus isolate from carp: genetic characterization reveals a novel picornavirus with two aphthovirus 2A-like sequences

Journal of General Virology, 2013
Picornaviruses have been isolated from a variety of hosts, mainly mammals and birds. Here, we describe the sequence analysis of carp picornavirus 1 (CPV-1) F37/06 that was isolated from an organ pool (heart, brain, liver) of a common carp (Cyprinus carpio). This carp perished after an accidental discharge of liquid manure into a fish pond and presented
Jeannette Lange, Marco Groth, Dieter Fichtner, Harald Granzow, Barbara Keller, Mario Walther, Matthias Platzer, Andreas Sauerbrei, Roland Zell   +8 more
openalex   +3 more sources

Evaluation of Direct Economic Losses Due to Foot and Mouth Disease Reported by the Epidemiological Surveillance System in Cameroon From 2009 to 2023. [PDF]

Vet Med Sci
The economic impact of FMD in Cameroon from 2009 to 2023 is determined by evaluating immediate, evident production losses, such as mortality losses, drop in milk production, and veterinary cost, which are usually faced by farmers. The expected total direct economic losses were USD 898,170.
Bayang HN, Mouiche Mouliom MM, Mpouam SE, Feussom Kameni JM, Moffo F, Kilekoung JPM.   +5 more
europepmc   +2 more sources

Assessment of Foot-and-Mouth Disease Trends in Türkiye Between 2005 and 2025. [PDF]

Transbound Emerg Dis
Foot‐and‐mouth disease (FMD) is a highly contagious viral illness that continues to threaten livestock health, productivity, and trade, particularly in countries like Türkiye where multiple FMD serotypes cocirculate. This study aimed to analyze the temporal and spatial distributions, serotype dynamics, and seasonal patterns of FMD in Türkiye between ...
Pedro Mil-Homens M, Arede M, Beltrán-Alcrudo D, Hovari M, Raizman E, Allepuz Palau A.   +5 more
europepmc   +2 more sources

Foot-and-Mouth Disease Virus Interserotypic Recombination in Superinfected Carrier Cattle

Pathogens, 2022
Viral recombination contributes to the emergence of novel strains with the potential for altered host range, transmissibility, virulence, and immune evasion.
Ian Fish, Carolina Stenfeldt, Edward Spinard, Gisselle N. Medina, Paul A. Azzinaro, Miranda R. Bertram, Lauren Holinka, George R. Smoliga, Ethan J. Hartwig, Teresa de los Santos, Jonathan Arzt   +10 more
doaj   +1 more source

Recovery of viral RNA and infectious foot-and-mouth disease virus from positive lateral-flow devices [PDF]

, 2014
Foot-and-mouth disease Virus (FMDV) is an economically important, highly contagious picornavirus that affects both wild and domesticated cloven hooved animals. In developing countries, the effective laboratory diagnosis of foot-and-mouth disease (FMD) is
Armson, Bryony, Bankowski, Bartlomiej M., Barnett, Paul V., Di Nardo, Antonello, Ferris, Nigel P., Fowler, Veronica L., King, Donald P., Mioulet, Valerie, Reid, Scott M., Valdazo-Gonzalez, Begoña, Wadsworth, Jemma   +10 more
core   +10 more sources

The long-lasting enigma of polycytidine (polyC) tract

PLoS Pathogens, 2021
Long polycytidine (polyC) tracts varying in length from 50 to 400 nucleotides were first described in the 5′-noncoding region (NCR) of genomes of picornaviruses belonging to the Cardio- and Aphthovirus genera over 50 years ago, but the molecular basis of
Velia Penza, Stephen J. Russell, Autumn J. Schulze   +2 more
doaj   +2 more sources

Oral and Faecal Viromes of New Zealand Calves on Pasture With an Idiopathic Ill-Thrift Syndrome. [PDF]

Transbound Emerg Dis
Since 2015, an idiopathic ill‐thrift syndrome featuring diarrhoea and, in some cases, gastrointestinal ulceration has been reported in weaned New Zealand dairy calves. Similar syndromes have been described in the British Isles and Australia, but investigations in New Zealand have yet to identify a specific cause. Notably, the viromes of affected calves
Grimwood RM, Darnley JA, O'Connell JP, Hunt H, Taylor HS, Lawrence KE, Abbott MBW, Jauregui R, Geoghegan JL.   +8 more
europepmc   +2 more sources

Into the Deep (Sequence) of the Foot-and-Mouth Disease Virus Gene Pool: Bottlenecks and Adaptation during Infection in Naïve and Vaccinated Cattle

Pathogens, 2020
Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected
Ian Fish, Carolina Stenfeldt, Rachel M. Palinski, Steven J. Pauszek, Jonathan Arzt   +4 more
doaj   +1 more source