Results 181 to 190 of about 1,204,736 (293)

A user-centric framework for harmonizing scientific name usage. [PDF]

Biodivers Data J
Berendsohn WG, Bánki O, Döring M, Fichtmueller D, Güntsch A, Hyam R, Meeus S, Müller A, Vanhoorne B.   +8 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Evaluation of the Osteogenic Potential of Apigenin via Inducing Autophagy: An In Vitro Study. [PDF]

Stem Cells Int
Khazaei M, Khodaei A, Bozorgi M, Khazaei MR, Bozorgi A.   +4 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

copick: An open dataset interface and toolkit for collaborative annotation and analysis of cryo-electron tomography data. [PDF]

Protein Sci
Ermel UH, Schwartz J, Zhao Z, Ji D, Peck A, Yu Y, Paraan M, Carragher B, Frangakis AS, Harrington KIS.   +9 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Development of a Simultaneous Analytical Method for Amines Corresponding to 10 Typical Nitrosamines

ACS Omega
Shohei Fukuda, Takehiro Hoshiyama, Kanako Kondo, Osamu Uchikawa   +3 more
doaj   +1 more source

Enhancing low-fat frankfurter texture and sensory properties with almond protein emulsion gels. [PDF]

Food Chem X
Hong SJ, Han JH, Keum DH, Han SG.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Differentiating Resistance from Formulation Failure: Isoniazid Instability and Poor Dissolution in Crushed Multi-Drug Paediatric Preparations. [PDF]

Pharmaceutics
Samsodien H, Winkler J, Aucamp M, Garcia-Prats AJ.   +3 more
europepmc   +1 more source