Results 171 to 180 of about 1,204,736 (293)

Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen. [PDF]

Nat Commun
Aagaard JB, Gandini R, Ballegaard AR, Jensen BK, Dorn B, Larsen AVB, Lenstrup A, Sønderholm M, Miehe M, Pfützner W, Jakob T, Andersen GR, Möbs C, Spillner E.   +13 more
europepmc   +1 more source

API documentation & API basecode

API documentation & API ...
openaire   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Mechanistic model of phase-transitioning therapeutics injected into poroelastic tissue for improved targeting of superficial tumors. [PDF]

Sci Rep
Adrianzen Alvarez DR, Orozco ESL, Ramanujam N, Mueller JL, Katz DF.   +4 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Bridging Material Variability and Tablet Performance: Optimization of Direct Compression Using Tensile Strength-Ejection Stress Mapping. [PDF]

Pharmaceutics
Casian T, Iurian S, Gâvan A, Negoi O, Marusca D, Marina A, Suciu M, Muntean D, Porfire A, Pop AL, Crișan S, Cauni D, Tomuță I.   +12 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Mapping nocturnal arousal across sleep and pain disorders. [PDF]

Sci Rep
Biabani N, Mendonça F, Mutti C, Drakatos P, Morgado-Dias F, Ravelo-García AG, Senel GB, Gretarsdottir H, Goadsby PJ, Thomas RJ, Bruni O, Ferri R, Parrino L, Rosenzweig I.   +13 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Simple and Practical Method for the Quantitative High-Sensitivity Analysis of N‑Nitroso Duloxetine in Duloxetine Drug Products Utilizing LC-MS/MS

ACS Omega
Shohei Fukuda, Yumiko Nakase, Kazuhide Imagaki, Kanako Kondo, Takahiko Taniguchi, Osamu Uchikawa   +5 more
doaj   +1 more source