Results 131 to 140 of about 215,818 (250)

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

What Is the Pterygomandibular Raphe? A Confluence of Fasciae Rather Than a Discrete Structure

Clinical Anatomy, EarlyView.
ABSTRACT The pterygomandibular raphe (PMR) has traditionally been described as a fibrous or tendinous band connecting the bucinator (BM) and superior pharyngeal constrictor (SPCM) muscles. However, recent evidence has questioned its existence. This study aimed to reevaluate the anatomy of the pterygomandibular region by preserving fascial continuity ...
Joe Iwanaga, Shion Hama, Keiko Fukino, Shogo Kikuta, Mi‐Sun Hur, Maria Cristina Manzanares Cespedes, Yoshio Ohyama, Masaya Akashi, Noritaka Komune, Hideaki Kamochi, Soichiro Ibaragi   +10 more
wiley   +1 more source

Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure. [PDF]

Dev Biol, 2021
Lesko AC, Keller R, Chen P, Sutherland A.   +3 more
europepmc   +1 more source

Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source

Assessment of the quality of root canal obturation of teeth with destructive forms of periodontitis using Silpex (SEM studies)

Эндодонтия Today
AIM. To evaluate the effectiveness of using the material Sealpex with gutta-percha pins using the lateral condensation method for permanent obturation of the root canals of teeth with periapical pathology and pathologically destroyed apical constriction ...
V. V. Glinkin, V. V. Glinkina, I. V. Chaikovskaya, M. A. Gasbanov, A. S. Karnaeva, N. N. Fedotova   +5 more
doaj   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II.

, 2018
The tumor suppressor Adenomatous polyposis coli (APC) is a negative regulator of Wnt signaling and functions in cytoskeletal organization. Disruption of human APC in colonic epithelia initiates benign polyps that progress to carcinoma following ...
Lauren M. Thorpe (5062955), Sandra G. Zimmerman (5062964), Vilma R. Medrano (5062958), Carolyn A. Mallozzi (5062961), Brooke M. McCartney (1247025)   +4 more
core   +1 more source

Jaw‐specific stem cell dynamics are associated with distinct enamel architecture in mouse incisors

Developmental Dynamics, EarlyView.
Abstract Background The continuously growing mouse incisor serves as a model for stem cell‐driven tooth renewal. Although mice possess maxillary and mandibular incisors, most studies have focused on the mandible. Potential differences in structure and renewal between these serially homologous organs remain insufficiently characterized.
Elias Shahin, Jihan Asmar, Sanako Takano, Jimmy K. Hu, Amnon Sharir   +4 more
wiley   +1 more source

New‐Generation Integrated Devices: Multiple‐Energy Utilization and Integration Systems Based on Perovskite Photovoltaics

EcoEnergy, EarlyView.
This review highlights emerging integrated energy systems based on perovskite photovoltaics, including PSC–thermoelectric, photovoltaic–electrochemical, self‐charging, and building‐integrated architectures. By coupling multiple energy conversion and storage pathways, these multifunctional platforms enable enhanced solar utilization, improved stability,
Yihuai Huang, Wenguang Zhang, Yuchen Xiong, Zijun Yi, Changkai Huang, Qinghui Jiang, Abdul Basit, Guibin Shen, Yubo Luo, Xin Li, Junyou Yang   +10 more
wiley   +1 more source

[Electroodontometric determination of location of apical constriction in root canal].

Stomatoloski glasnik Srbije, 1991
Electronic odontometer (Goof, Denmark) was used in clinical investigation of 169 root canals of 138 teeth, treated for different endodontic reasons. A removable plastic collar was fixed to endocanal electrode (K-reamer) on which the exact length was signalized as apical constriction, followed by radiographic control.
M, Pajić, M, Vujasković, V, Ivanović
openaire   +1 more source