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Development and validation of an HPTLC method for apigenin 7-O-glucoside in chamomile flowers and its application for fingerprint discrimination of chamomile-like materials

open access: yesJournal of Pharmaceutical and Biomedical Analysis, 2015
Brewed tea of chamomile flowers (Matricaria recutita L.) (Asteraceae) has been extensively consumed for centuries due to either its pleasant taste or medicinal purposes. On the other hand, the major problem is difficulty in distinguishing the genuine specimen when supplying chamomile through nature-picking.
Etil Guzelmeric   +2 more
exaly   +4 more sources
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Apigenin-7-O-glucoside oxidation catalyzed by P450-bioinspired systems

Journal of Inorganic Biochemistry, 2017
Apigenin-7-O-glucoside (A7G) is the main flavonoid of Bidens gardneri Bak., a Brazilian plant with wide application in folk medicine. Despite the popular use of this plant, its biological effects are not completely known. This work tested the 5,10,15,20-tetrakis(pentafluorophenyl)porphyrin iron(III) and manganese(III) chloride (Fe(TFPP)Cl and Mn(TFPP ...
Lucas B. Bolzon   +6 more
openaire   +2 more sources

Apigenin 7-O-glucoside promotes cell apoptosis through the PTEN/PI3K/AKT pathway and inhibits cell migration in cervical cancer HeLa cells

Food and Chemical Toxicology, 2020
Epidemiologic evidence promote the inclusion of flavones in diet due to their inhibitory effects on certain types of cancers, particularly in women. Among the naturally occurring plant flavonoids, Apigenin 7-O-glucoside (AGL) is endowed with anti-inflammatory, anti-oxidant, and anti-cancer activities. However, its mechanism of action on cervical cancer,
Miao-Miao, Liu   +6 more
openaire   +2 more sources

From Extraction to Ocular Delivery: An Integrated Approach Using Apigenin and Apigenin 7-O-Glucoside Nanosuspensions to Treat Corneal Neovascularization

Corneal neovascularization (CNV) is a vision-threatening condition characterized by the pathological ingrowth of blood vessels. While corticosteroids and anti-VEGF agents are standard treatments, their prolonged use is associated with significant ocular side effects.
Eren Aytekin   +10 more
openaire   +1 more source

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