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The Therapeutic Potential of Apigenin [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Several plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic diseases. The largest group of naturally-occurring polyphenols are the flavonoids, including apigenin.
Bahare Salehi   +2 more
exaly   +6 more sources

Protective Roles of Apigenin Against Cardiometabolic Diseases: A Systematic Review

open access: yesFrontiers in Nutrition, 2022
Apigenin is a flavonoid with antioxidant, anti-inflammatory, and anti-apoptotic activity. In this study, the potential effects of apigenin on cardiometabolic diseases were investigated in vivo and in vitro.
Yajie Xu, Xue Li
exaly   +3 more sources

Preparation, characterization and antitumor activity evaluation of apigenin nanoparticles by the liquid antisolvent precipitation technique

open access: yesDrug Delivery, 2017
The present work aimed to apply the liquid antisolvent precipitation (LAP) method for preparing the apigenin nanoparticles and thereby improving the solubility and bioavailability of apigenin.
Weiwei Wu, Lingling Wang, Huimei Wang
exaly   +2 more sources

Neuroprotective, Anti-Amyloidogenic and Neurotrophic Effects of Apigenin in an Alzheimer’s Disease Mouse Model

open access: yesMolecules, 2013
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by extracellular senile plaques and intracellular neurofibrillary tangles in the brain.
Jun‐Li Wang, Rui Liu
exaly   +3 more sources

Apigenin accumulation and expression analysis of apigenin biosynthesis relative genes in celery

open access: yesScientia Horticulturae, 2014
Apigenin, a naturally occurring plant flavone, abundantly present in common fruits and vegetables, is recognized as a bioactive flavonoid shown to possess anti-inflammatory, antioxidant, and anticancer properties. Apigenin content in different tissues and during leaf development was analyzed in celery cv. Shanghai yellow heart and cv. Ventura. Apigenin
Jun Yan, Weihong Gu, Weimin Zhu
exaly   +2 more sources

Facilitating Reparative Dentin Formation Using Apigenin Local Delivery in the Exposed Pulp Cavity

open access: yesFrontiers in Physiology, 2021
Apigenin, a natural product belonging to the flavone class, affects various cell physiologies, such as cell signaling, inflammation, proliferation, migration, and protease production.
Yam Prasad Aryal   +15 more
doaj   +1 more source

Recent advancement in bioeffect, metabolism, stability, and delivery systems of apigenin, a natural flavonoid compound: challenges and perspectives

open access: yesFrontiers in Nutrition, 2023
Apigenin is a bioflavonoid compound that is widely present in dietary plant foods and possesses biological activities that protect against immune, cardiovascular, and neurodegenerative diseases and cancer.
Peng Chen   +4 more
doaj   +1 more source

Bioconversion of apigenin-7-O-β-glucoside in aqueous two-phase system [PDF]

open access: yesActa Periodica Technologica, 2005
The study is concerned with the conversion of apigenin-7-O-β-glucoside into apigenin in polyethylene glycol 6000 / dextran 20000 aqueous two-phase system by β-glucosidase.
Ilić Sanja M.   +4 more
doaj   +1 more source

Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages. [PDF]

open access: yesPLoS ONE, 2014
Apigenin is a non-toxic natural flavonoid that is abundantly present in common fruits and vegetables. It has been reported that apigenin has various beneficial health effects such as anti-inflammation and chemoprevention. Multiple studies have shown that
Xiaoxuan Zhang   +3 more
doaj   +1 more source

Apigenin Ameliorates Scopolamine-Induced Cognitive Dysfunction and Neuronal Damage in Mice

open access: yesMolecules, 2021
We investigated the protective effect and mechanisms of apigenin against cognitive impairments in a scopolamine-injected mouse model. Our results showed that intraperitoneal (i.p.) injection of scopolamine leads to learning and memory dysfunction ...
Yeojin Kim   +4 more
doaj   +1 more source

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