Results 11 to 20 of about 39,255 (266)

Apigenin-7-O-glucoside versus apigenin: insight into the modes of anticandidal and cytotoxic actions [PDF]

open access: yesEXCLI journal, 2017
EXCLI Journal; 16:Doc795; ISSN 1611 ...
Ivanov, Marija   +11 more
openaire   +7 more sources

Inhibitory Effects of Apigenin on Tumor Carcinogenesis by Altering the Gut Microbiota

open access: yesMediators of Inflammation, 2020
The flavonoid apigenin is common to many plants. Although the responsible mechanisms have yet to be elucidated, apigenin demonstrates tumor suppression in vitro and in vivo.
Shichang Bian   +3 more
doaj   +2 more sources

Apigenin and apigenin-derivatives from artichokes: urine excretion in humans

open access: yes, 2011
Apigenin and apigenin glycosides are the main flavonoids in artichokes. Thus, their 24 h-urinary excretion was investigated, as a marker of absorption, in six women after consumption of two steamed artichokes. No enzymes treatment was performed and the urine metabolites were investigated by HPLC-MS/MS.
RICIPUTI, YLENIA   +3 more
core   +4 more sources

Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways

open access: yesPPAR Research, 2021
Objective. The aim of this study is to confirm the hepatocellular protective functions of apigenin and the molecular mechanism on liver fibrosis in mice. Methods. Carbon tetrachloride (CCl4) and bile duct ligature (BDL) mouse fibrosis models were used to
Jie Ji   +7 more
doaj   +2 more sources

Apigenin Induces Apoptosis and Inhibits Migration in Human Cholangiocarcinoma Cells

open access: yesToxics
Cholangiocarcinoma (CCA) is a rare and highly aggressive cancer of the biliary tract, associated with poor clinical outcomes due to late diagnosis, extensive metastasis, drug resistance, and limited treatment options.
Mayurachat Kaewmanee   +2 more
doaj   +2 more sources

Apigenin Provides Structural Protection to Human Fibrinogen against Nitrosative Stress: Biochemical and Molecular Insights

open access: yesBiomolecules
Background: Peroxynitrite (ONOO−) is an oxidant linked with several human pathologies. Apigenin, a natural flavonoid known for its health benefits, remains unexplored in relation to ONOO− effects.
Aisha Farhana   +5 more
doaj   +2 more sources

Labeling of apigenin with 131I and bioactivity of 131I-apigenin in male and female rats

open access: yesJournal of Radioanalytical and Nuclear Chemistry, 2009
Apigenin (4′,5,7-trihydroxyflavone), one of the most common flavonoids, has been shown to possess a variety of biological activities including tumor growth inhibition and chemopreventation. In the present study, apigenin was labeled with 131I using iodogen method and investigated of its bioactivity.
Seyitoglu B.   +2 more
openaire   +3 more sources

Apigenin Cocrystals: From Computational Prescreening to Physicochemical Property Characterization [PDF]

open access: yes, 2023
Apigenin (4′,5,7-trihydroxyflavone, APG) has many potential therapeutic benefits; however, its poor aqueous solubility has limited its clinical applications. In this work, a large scale cocrystal screening has been conducted, aiming to discover potential
Jay Makadia (15212413)   +5 more
core   +2 more sources

Untargeted metabolomics based prediction of therapeutic potential for apigenin and chrysin [PDF]

open access: yes, 2022
Flavonoids belong to the polyphenol superfamily and present in our foods derived from natural sources including fruits and vegetables. Apigenin and Chrysin, prominent flavonoids have been demonstrated to have systemic benefits.
Angela, Leontyev   +7 more
core   +1 more source

Spasmolytic and Uroprotective Effects of Apigenin by Downregulation of TGF-β and iNOS Pathways and Upregulation of Antioxidant Mechanisms: In Vitro and In Silico Analysis

open access: yesPharmaceuticals, 2023
Apigenin is a phytochemical obtained from Chamomilla recutita. Its role in interstitial cystitis is not yet known. The present study is aimed at understanding the uroprotective and spasmolytic effects of apigenin in cyclophosphamide-induced interstitial ...
Saima   +7 more
doaj   +1 more source

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