Results 31 to 40 of about 39,255 (266)

Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition

Molecules, 2015
Apigenin, a nonmutagenic flavonoid, has been found to have antitumor properties and is therefore particularly relevant for the development of chemotherapeutic agents for cancers.
Md. Abul Hasnat, Mehnaz Pervin, Ji Hong Lim, Beong Ou Lim   +3 more
doaj   +1 more source

Development of a novel apigenin prodrug programmed for alkaline-phosphatase instructed self-inhibition to combat cancer

, 2023
International audienceElevated levels of alkaline phosphatase (ALP) in the tumor microenvironment (TME) are a hallmark of cancer progression and thus inhibition of ALP could serve as an effective approach against cancer.
Dimitrios Diamantis, Christina Papaemmanouil, Andrej Babic, Eleftherios Paraskevas Tzakos, Gupta, S., Theodoros Rampias, Isabelle Fournier, Andreas G. Tzakos, Tzakos, E. P., Diamantis, D., Sanjay Gupta, Kushwaha, P. P., Thomaidis, N. S., Zoi Kanaki, Tsiailanis, A. D., Papaemmanouil, C., Fournier, Isabelle, Nikolaos S. Thomaidis, Salzet, Michel, Karakurt, S., Serdar Karakurt, Kanaki, Z., Simona Golic Grdadolnik, Golic Grdadolnik, S., Rampias, T., Shankar, E., Eswar Shankar, Babic, A., Maria-Christina Nika, Prem Prakash Kushwaha, Tzakos, A. G., Antonios D. Tsiailanis, Michel Salzet, Nika, M. C.   +33 more
core   +1 more source

Anti-inflammatory and Anti-apoptotic Potentials of Apigenin against Liver Injury Induced by Ischemia-Reperfusion in Rats

Bulletin of Faculty of Pharmacy Cairo University, 2019
Apigenin is a dietary flavonoid that exists copiously in several herbs and vegetables. It exhibits anti-inflammatory, anti-mutagenesis, anti-proliferative and antioxidant properties.
Dalia El-Tanbouly, Hala Zaki, Rania Abdelsalam, Aya Zaki   +3 more
doaj   +1 more source

Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin

, 2023
Apigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables. It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory, anticancer, and antibacterial effects.
Thomas, Shilu Deepa, Niraj Kumar Jha, Shilu Deepa Thomas, Saurabh Kumar Jha, Jha, Saurabh Kumar, Bassem Sadek, Shreesh Ojha, Sadek, Bassem, Jha, Niraj Kumar, Ojha, Shreesh   +9 more
core   +1 more source

Inhibition of Epstein-Barr virus reactivation by the flavonoid apigenin [PDF]

, 2017
[[abstract]]Background: Lytic reactivation of EBV has been reported to play an important role in human diseases, including NPC carcinogenesis. Inhibition of EBV reactivation is considered to be of great benefit in the treatment of virus-associated ...
Wu, CC;Fang, CY;Cheng, YJ;Hsu, HY;Chou, SP;Huang, SY;Tsai, CH;Chen, JY
core   +2 more sources

Anti-Oxidative and Anti-Apoptotic Effects of Apigenin on Number of Viable and Apoptotic Blastomeres, Zona Pellucida Thickness and Hatching Rate of Mouse Embryos [PDF]

International Journal of Fertility and Sterility, 2018
Background Apigenin is a plant-derived compound belonging to the flavonoids category and bears protective effects on different cells. The aim of this study was to evaluate the effect of apigenin on the number of viable and apoptotic blastomeres, the ...
Manouchehr Safari, Houman Parsaie, Hamid Reza Sameni, Mohammad Reza Aldaghi, Sam Zarbakhsh   +4 more
doaj   +1 more source

Development of a Novel Apigenin Dosage form as a Substitute for the Modern Triple Antithrombotic Regimen

Molecules, 2023
The simultaneous administration of three antiplatelet agents has been proposed as an efficient strategy for the secondary prevention of atherothrombotic events and is included in the European guidelines. However, this strategy presented an increased risk
Antonios D. Tsiailanis, Constantinos C. Tellis, Paraskevi Papakyriakopoulou, Androniki D. Kostagianni, Vasileios Gkalpinos, Christos M. Chatzigiannis, Nikolaos Kostomitsopoulos, Georgia Valsami, Alexandros D. Tselepis, Andreas G. Tzakos   +9 more
doaj   +1 more source

Apigenin-7-O-glucoside versus apigenin

, 2017
EXCLI Journal;Vol.
Smiljkovic, Marija, Stanisavljevic, Danijela, Stojkovic, Dejan, Petrovic, Isidora, Marjanovic Vicentic, Jelena, Popovic, Jelena, Golic Grdadolnik, Simona, Markovic, Dejan, Sanković-Babić, Snežana, Glamoclija, Jasmina, Stevanovic, Milena, Sokovic, Marina   +11 more
openaire   +2 more sources

Efficient Synthesis and In Vitro Hypoglycemic Activity of Rare Apigenin Glycosylation Derivatives

, 2023
Apigenin is a natural flavonoid with significant biological activity, but poor solubility in water and low bioavailability limits its use in the food and pharmaceutical industries.
Li, Jiayao, Lin Zhao, Zhang, Sen, Yujie Zhu, Mu, Wen, Yan, Ke, Zhao, Lin, Pei, Yuqiong, Yuqiong Pei, Xia, Mingjun, Jinao Duan, Guoxin Zhang, Jing Han, Ke Yan, Han, Jing, Duan, Jinao, Jiayao Li, Sen Zhang, Mingjun Xia, Zhu, Yujie, Zhang, Guoxin, Wen Mu   +21 more
core   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source