Results 41 to 50 of about 39,255 (266)

Apigenin directly interacts with and inhibits topoisomerase 1 to upregulate CD26/DPP4 on colorectal carcinoma cells

open access: yesFrontiers in Pharmacology, 2022
Introduction: CD26/dipeptidyl peptidase IV (DPP4) is a cell-surface glycoprotein present on most epithelial cells that modulates the local response to external signals. We have previously shown that the dietary flavone apigenin (4′,5,7-trihydroxyflavone)
Julia E. Fux   +4 more
doaj   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang   +11 more
wiley   +1 more source

Apigenin induced apoptosis in ANA-1 cells.

open access: yes, 2014
A typical DNA ladder in ANA-1 cells was observed after being treated with 50 μM apigenin for 48 h. Lanes: 1) control; 2) 12.5 μM apigenin; 3) 25 μM apigenin; 4) 50 μM apigenin.
Weigan Shen (539771)   +5 more
core   +1 more source

Interactions of delivery systems modulating the digestibility of plant‐based proteins

open access: yesFood Biomacromolecules, EarlyView.
Abstract Plant‐based proteins are gaining interest as sustainable alternatives to animal‐derived proteins, but their digestibility is often lower and strongly influenced by protein structure, processing history, and food‐matrix interactions. This review critically examines how emulsions, hydrogels, micro‐ and nanoparticles, micelles, liposomes ...
Samina Kauser   +5 more
wiley   +1 more source

An Improved Synthesis of Apigenin

open access: yesJournal of Chemical Research, 2015
Two routes for the synthesis of the flavone apigenin are described. In the first, taxicatigenin was converted to 2-hydroxy-4,6-dimethoxyacetophenone and then by condensation with anisaldehyde to 2′-hydroxy-4,4′,6′-trimethoxychalcone. The latter was cyclised with iodine and demethylated with pyridine hydrochloride to form apigenin in 53% overall yield ...
Qian Wang   +6 more
openaire   +1 more source

Apigenin directly binds to RPS9.

open access: yes, 2013
(A) Apigenin-binding proteins were purified from whole cell extracts of HT-29 cells with apigenin-fixed (+) or empty (-) beads, and detected by silver staining. Mass spectrometry analysis identified RPS9 as an apigenin-binding protein.
Tomoyuki Taniguchi (337403)   +5 more
core   +1 more source

Valorization of Citrus Waste for Recovery of Nutritional and Bioactive Compounds: A Comprehensive Review

open access: yesFuture Postharvest and Food, EarlyView.
The various citrus wastes, including the citrus fruit peels, pulp remaining after extraction of juice, and seeds, are the sources of bioactive compounds. The waste parts of oranges, lemons, limes, grapefruits, and mandarins contain the bioactive compounds, flavonoids, ascorbic acid, essential oils, and carotenoids.
Monika   +4 more
wiley   +1 more source

Physicochemical, Functional, and Health‐Promoting Properties of Processed Nettle (Urtica Dioica) Leaves: A Review

open access: yesFuture Postharvest and Food, EarlyView.
Stinging nettle (Urtica dioica L.) leaves are a nutrient‐dense source of proteins, dietary fiber, chlorophylls, carotenoids, and phenolic compounds. Processing technologies enable the production of powders and extracts for incorporation into bakery, beverage, dairy, and nutraceutical products; however, challenges remain regarding sensory quality ...
Mary Nkongho Tanyitiku   +2 more
wiley   +1 more source

Three-Dimensional Printing of an Apigenin-Loaded Mucoadhesive Film for Tailored Therapy to Oral Leukoplakia and the Chemopreventive Effect on a Rat Model of Oral Carcinogenesis

open access: yesPharmaceutics, 2022
Oral leukoplakia, which presents as white lesions in the oral cavity, including on the tongue, is precancerous in nature. Conservative treatment is preferable, since surgical removal can markedly reduce the patient’s quality of life. In the present study,
Hiroyuki Takashima   +5 more
doaj   +1 more source

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