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Apigenin as an anticancer agent
Phytotherapy Research, 2020 AbstractApigenin is an edible plant‐derived flavonoid that has been reported as an anticancer agent in several experimental and biological studies. It exhibits cell growth arrest and apoptosis in different types of tumors such as breast, lung, liver, skin, blood, colon, prostate, pancreatic, cervical, oral, and stomach, by modulating several signaling ...
Bahare Salehi +2 more
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The Therapeutic Potential of Apigenin [PDF]
International Journal of Molecular Sciences, 2019 Several plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic diseases. The largest group of naturally-occurring polyphenols are the flavonoids, including apigenin.
Antonello Santini +2 more
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Apigenin accumulation and expression analysis of apigenin biosynthesis relative genes in celery
Scientia Horticulturae, 2014 Apigenin, a naturally occurring plant flavone, abundantly present in common fruits and vegetables, is recognized as a bioactive flavonoid shown to possess anti-inflammatory, antioxidant, and anticancer properties. Apigenin content in different tissues and during leaf development was analyzed in celery cv. Shanghai yellow heart and cv. Ventura. Apigenin
Weimin Zhu, Jun Yan, Weihong Gu
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Evaluation of Properties of Apigenin and [G-3H]Apigenin and Analytic Method Development
Journal of Pharmaceutical Sciences, 1997This study provides baseline data and analytical methods to assist in the evaluation of apigenin, a plant flavonoid with promising chemopreventive activity against skin cancer. Apigenin was freely soluble in dimethylsulfoxide (> 100 mg/mL), but it had low solubility (0.00135-1.63 mg/mL) in all the other solvents and surfactants tested, especially in ...
B, Li, D H, Robinson, D F, Birt
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On the Accumulation of Apigenin in Chamomile Flowers
Planta Medica, 1990By preparing and analysing extracts of fresh chamomile flowers from outdoor and greenhouse cultures, it was possible to show that apigenin does not actually occur in living chamomile flowers. Apigenin is the result of post-harvest processes converting apigenin 7-glycoside and its derivatives into the aglycone.
A, Schreiber, R, Carle, E, Reinhard
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Journal of Chromatography B, 2019
A new ultra-high performance liquid chromatography-mass spectrometry-mass spectrometry (UHPLC-MS/MS) system has been formulated for the resolution of closely related drugs apigenin (API, a bioflavinoid) and prednisolone (PRD) from their mixture. This developed method comprised of a "BEH™ C18 column (50 mm × 2.1 mm, 1.7 μm)" using acetonitrile and 0.1 ...
Ehab M, Elzayat +7 more
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A new ultra-high performance liquid chromatography-mass spectrometry-mass spectrometry (UHPLC-MS/MS) system has been formulated for the resolution of closely related drugs apigenin (API, a bioflavinoid) and prednisolone (PRD) from their mixture. This developed method comprised of a "BEH™ C18 column (50 mm × 2.1 mm, 1.7 μm)" using acetonitrile and 0.1 ...
Ehab M, Elzayat +7 more
openaire +2 more sources
Apigenin, a flavonoid naturally found in many vegetables, fruits, and medicinal plants, possesses strong antioxidant properties. Apigenin is produced in plants through flavonoid biosynthesis, starting with phenylalanine. Thanks to its three hydroxyl groups, it reduces cellular damage by scavenging free radicals.
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