Results 171 to 180 of about 114,772,772 (250)

Structural origins of species-specific differences in TRPV2 activation. [PDF]

Nat Commun
Fricke TC, Pumroy RA, Rocereta JA, De Jesús-Pérez JJ, Oprita G, Meyer MJA, Herzog C, Echtermeyer FG, Hill K, Leffler A, Moiseenkova-Bell VY.   +10 more
europepmc   +1 more source

Developing a social vulnerability index for antenatal care screening of risk for adverse maternal and perinatal outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Social determinants of health influence maternal and perinatal outcomes, yet tools to operationalize these risks in clinical care remain scarce. We aimed to study social determinants in Brazilian pregnant women and develop a social vulnerability index (SVI) that could correlate with pregnancy and perinatal outcomes.
Gabriel Q. Rippel, Renato T. Souza, Jussara Mayrink, Maria J. Miele, Rafael B. Galvao, Maria L. Costa, Francisco E. Feitosa, Edilberto A. Rocha Filho, Debora F. Leite, Ricardo P. Tedesco, Danielly S. Santana, Karayna G. Fernandes, Janete Vettorazzi, Iracema M. Calderon, Jose G. Cecatti   +14 more
wiley   +1 more source

A curated benchmark for cofolding models on kinase conformational states. [PDF]

NPJ Drug Discov
Sun K, Head-Gordon T.
europepmc   +1 more source

Reassessing the role of antiphospholipid antibodies in placental‐mediated adverse pregnancy outcomes in systemic lupus erythematosus: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine how different antiphospholipid antibody (aPL) profiles influence placental‐mediated adverse pregnancy outcomes (APOs) in women with systemic lupus erythematosus (SLE). Methods This retrospective cohort study included 245 pregnant women with SLE and 490 controls from a single center.
Meng Jiang, Yanling Chang, Ning Zhang, Wen Di, Jiayue Wu   +4 more
wiley   +1 more source

Virtual Screening and Molecular Dynamics Simulations Identifying Natural Product-Derived Cathepsin K Inhibitors as Potential Therapeutics for Osteoporosis. [PDF]

Int J Mol Sci
Tarathipayakul T, Ravikumar Y, Srichairatanakool P, Khowsathit J, Srichairatanakool S.   +4 more
europepmc   +1 more source

Menopause hormone therapy in women with cardiovascular risk factors or established ischemic heart disease: A joint FIGO and WHF position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto, Martha Gulati, Suvarna S. Khadilkar, Angela H. E. M. Maas, Federica Frezet, Gláucia Maria Moraes de Oliveira, Andrea R. Genazzani, Hema Divakar, Athena Poppas, on behalf of the World Heart Federation (WHF) and the International Federation of Gynecology and Obstetrics (FIGO)   +9 more
wiley   +1 more source

Agonist Binding Reshapes the Kinetic Landscape and Allosteric Communication of APLNR Toward Activation-Competent States. [PDF]

Int J Mol Sci
Dai H, Zhu JY, Zhang BD, Liu MT, Sang P, Yang LQ.   +5 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Interaction between the number of KIV2 repeats and the cholesterol content of an Lp(a) particle: What to do with these novel data? [PDF]

J Lipid Res
Reyes-Soffer G, Ginsberg HN.
europepmc   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source