Results 111 to 120 of about 6,750 (198)

Expression of HIV-1 Vif and Human APOBEC3G with a Bicistronic Vector

, 2011
Novel targets against HIV-1 are booming recently. APOBEC3G has the potential to inhibit the replication of HIV-1, while its antiviral activity is counteracted by Vif.
Yi Zeng, Xiao Li Wang, Xiao Na Sun, Ze Lin Li, Yi Shu Yang, Di Liu, Si Si Shen   +6 more
core   +1 more source

The role of APOBEC3G in acute and early HIV-1 subtype C infection. [PDF]

, 2014
Thesis (Ph.D.)-University of KwaZulu-Natal, Durban, 2014.Introduction APOBEC3G and other related cellular cytosine deaminase family members have potent antiviral activity.
Reddy, Kavidha.
core   +1 more source

Die Rolle von APOBEC3G in der angeborenen Immunität gegenüber HIV-Infektionen primärer Zellen [PDF]

, 2009
In the past few years the regulation of HIV-1 replication by cellular cofactors has been a major topic of ongoing research. These factors potentially represent new targets for antiviral therapy as resistance will be minimized.
Heinzelmann, Anna
core  

Cellular interactions of virion infectivity factor (Vif) as potential therapeutic targets: APOBEC3G and more?

, 2006
© 2007 Ingenta.Vif is an HIV accessory protein whose primary function is to negate the action of APOBEC3G, a naturally occurring cellular inhibitor of HIV replication.
Davis, A., Burrell, Christopher, Li, P., Feng, Feng, Carr, J., Feng, F., Li, Peng, Davis, Adam, Burrell, C., Carr, Jill   +9 more
core   +1 more source

Optimization of the apolipoprotein B mRNA editing enzyme catalytic polypeptidelike-3G (APOBEC3G) gene to enhance its expression in Escherichia coli

, 2020
BACKGROUND Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like-3G (APOBEC3G) can abolish HIV infection by inducing lethal mutations in the HIV genome.
Avissa, Rizkyana, Widyaningtyas, Silvia Tri, Bela, Budiman   +2 more
core   +1 more source

Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain

Nature Communications
APOBEC3G, part of the AID/APOBEC cytidine deaminase family, is crucial for antiviral immunity. It has two zinc-coordinated cytidine-deaminase domains.
Hanjing Yang, Josue Pacheco, Kyumin Kim, Ayub Bokani, Fumiaki Ito, Diako Ebrahimi, Xiaojiang S. Chen   +6 more
doaj   +1 more source

Different interaction between HIV-1 Vif and its cellular target proteins APOBEC3G/APOBEC3F [PDF]

, 2010
We examined a series of site-directed point mutants of human immunodeficiency virus type 1 (HIV-1) Vif for their interaction with cellular anti-viral factors APOBEC3G/APOBEC3F.
Yamashita, Tomoki, 90151901, 足立, 昭夫, 三宅, 在子, Adachi, Akio, Miyake, Ariko, 内山, 恒夫, アダチ, アキオ, 90127043, 20548622, ヤマシタ, トモキ, 野間口, 雅子, ミヤケ, アリコ, Nomaguchi, Masako, ノマグチ, マサコ, ナガオ, タミコ, 153171/profile-ja.html, 1594, 80452647, 385, Uchiyama, Tsuneo, 246, ウチヤマ, ツネオ, Nagao, Tamiko, 60165/profile-ja.html, 1604   +25 more
core  

Vif and Apobec3G in the innate immune response to HIV: a tale of two proteins

, 2009
It is now 26 years after the first published report on HIV, and the global epidemic continues unabated, with estimates of over 33 million people currently infected, worldwide.
Sheehy, Ann M., Farrow, Melissa Ann
core   +1 more source

Prevalence of HBsAg among Moroccan HIV-1 infected patients and APOBEC3G variant frequencies in HIV-1/HBV co-infection

Journal of Infection in Developing Countries
Introduction: Human immunodeficiency virus (HIV) / hepatitis B virus (HBV) causes higher rates of liver disease compared to infection with just one virus.
Imane Belbacha, Rajae Bensghir, Kamal Filali Marhoum, Majda Laboudi, Khadija Hajoutt, Elmir Elharti, Khalid Sadki, Hicham Oumzil   +7 more
doaj   +1 more source

APOBEC3G Gene [PDF]

, 2020
openaire   +1 more source