Results 231 to 240 of about 121,312 (312)

Alteration in oral and non‐oral tissues in ligature‐induced periodontitis mice with the Alzheimer's disease risk factor APOE4

European Journal of Oral Sciences, EarlyView.
Abstract The APOE4 gene, particularly the ε4 allele, is linked to susceptibility to Alzheimer's disease, and periodontitis can cause pathological changes in multiple organs, but combined effects of these conditions and the impact of tumor necrosis factor (TNF)‐α regulation on the combined effects remain unclear.
Ae Ri Kim, Yun‐Jung Yoo, Eun‐Jung Bak   +2 more
wiley   +1 more source

In Silico ApoE Isoform Interactions with Methylmercury (MeHg) and In Vivo MeHg Intoxication Effects on Epididymal White Fat Tissue and Liver Function in Young ApoE Knockout Mice. [PDF]

Chem Res Toxicol
Lopes SC, Monteiro VKF, Leocádio PCL, Rodrigues MVF, Maciel d'Auriol Souza M, de Paiva MJN, Zandonadi F, Sussulini A, Raposo R, da Silva FL, Zampieri D, Coppi AA, Martins AMA, Alvarez-Leite J, Lopes da Silva ÁR, Monteiro NKV, Oriá RB.   +16 more
europepmc   +1 more source

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

Journal of Internal Medicine, EarlyView.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca, Elias Björnson, Laura D'Erasmo, Alessia Di Costanzo, Simone Bini, Ilenia Minicocci, Daniele Tramontano, Stella Covino, Giuseppe Ciarlo, Manuela Lombardi, Sanni Söderlund, Niina Matikainen, Linda Andersson, Martin Adiels, Marja‐Riitta Taskinen, Chris J. Packard, Jan Borén   +16 more
wiley   +1 more source

A POSTN⁺ CAF/APOE⁺ TAM Axis is Associated with Tumor Progression and Potential Immunotherapy Resistance in Laryngeal Squamous Cell Carcinoma. [PDF]

Int J Gen Med
Ma K, Tian J, Wu H, Wang S, Ni HS.
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Association between serum lipid-apolipoprotein alterations and soluble syndecan-1 dynamics in sepsis: impact of apolipoprotein E isoforms. [PDF]

Biochem Biophys Rep
Shimizu R, Akahane S, Suzuki H, Matsuura H, Uematsu Y, Iimura W, Ishimine N, Yamauchi K.   +7 more
europepmc   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

PACAP and Maxadilan (PAC1 Agonist) Influence Plaque Progression, Migratory Ability, and Mitochondrial Morphology and Dynamics in Vascular Smooth Muscle Cells. [PDF]

Cells
Brauschke J, Schütz LM, Bonaterra GA, Kinscherf R, Schwarz A.   +4 more
europepmc   +1 more source

La ''causa'' nel pensiero dei giuristi di ''common law''

Gorla, Gino, Gorla, Gino
openaire   +1 more source