Results 171 to 180 of about 131,925 (308)

Structural and resting-state MRI detects regional brain differences in young and mid-age healthy APOE-e4 carriers compared with non-APOE-e4 carriers

, 2016
The presence of the e4 allele of the apolipoprotein E (APOE) gene is the best-known genetic risk factor for Alzheimer's disease. In this study, we investigated the link between functional and behavioural differences and regional brain volume and cortical
Sarah King (4460617), Jennifer Rusted (4460485), Simon L Evans (16039634), Naji Tabet (4461808), Nicholas Dowell (4462081), Paul S Tofts (16048253)   +5 more
core  

<i>ECH1</i>-Deficiency-Mediated Polyunsaturated Fatty Acid Accumulation Promotes Vascular Smooth Muscle Cell Ferroptosis and Chronic-Kidney-Disease-Associated Plaque Vulnerability. [PDF]

Research (Wash D C)
Bi X, Zhou J, Liu L, Chen Z, Liang B, Tian S, Xiong J, Lan Q, Lv L, Li Y, Xiao T, He T, Zhang J, Nie L, Zhao J.   +14 more
europepmc   +1 more source

'Quantum mechanics' and 'scientific explanation' an explanatory strategy aiming at providing 'understanding'

, 2008
Empirical studies persistently indicate that the usual explanatory strategies used in quantum mechanics (QM) instruction fail, in general, to yield understanding. In this study, we propose an instructional intervention, which: (a) incorporates into its subject matter a critical comparison of QM scientific content with the fundamental epistemological ...
openaire   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Apolipoprotein E Gene ϵ4 Allele is Associated with Atherosclerosis in Multiple Vascular Beds

International Journal of General Medicine
Youni Lin, Min Yang, Qifeng Liu, Yufu Cai, Zhouhua Zhang, Chongfei Xu, Ming Luo Center for Cardiovascular Diseases, Meizhou People’s Hospital, Meizhou, People’s Republic of ChinaCorrespondence: Youni Lin, Center for Cardiovascular Diseases, Meizhou ...
Lin Y, Yang M, Liu Q, Cai Y, Zhang Z, Xu C, Luo M   +6 more
doaj  

APOE in subjective cognitive decline: a systematic review and meta-analysis. [PDF]

J Neurol
Alonge P, Baiamonte L, Gerardi G, Torrente A, Lo Mauro E, Veronese N, Labate A, Monastero R.   +7 more
europepmc   +1 more source

Link Between Obsessive-Compulsive Disorder and ApoE Gene Polymorphisms

Ayse Dondu,1 Metin Caliskan,2 Seda Orenay-Boyacioglu3 1Department of Psychiatry, Aydın Goverment Hospital, Aydin, 09010, Turkey; 2Department of Medical Biology, Faculty of Medicine, Usak University, Usak, 64000, Turkey; 3Department of Medical ...
Orenay-Boyacioglu S, Dondu A, Caliskan M
core  

Non‐Nutritive Artificial Sweeteners Aspartame and Acesulfame‐K Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease in Male Ldlr−/− Mice

iNew Medicine, EarlyView.
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu, Xiaohua Jiang, Jianping Weng, Suowen Xu   +3 more
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

<i>APOE</i>-associated lipid-handling macrophages in hepatocellular carcinoma: ligand-receptor communication and host <i>Apoe</i>-linked myeloid remodeling. [PDF]

Front Immunol
Wu T, Xin G, Zhou J, Wang X, Niu J.
europepmc   +1 more source