Results 171 to 180 of about 96,484 (269)

A reappraisal of APOE genetic effects on Alzheimer's disease risk in the Japanese population: a meta-analysis. [PDF]

Mol Neurodegener
Miyashita A, Hara N, Obinata A, Tsukie T, Hasegawa M, Ishiguro T, Kasuga K, Kikuchi M, Hashimoto T, Kanekiyo T, Ikeuchi T.   +10 more
europepmc   +1 more source

Alcohol consumption and cognitive function: A systematic review and dose–response meta‐analysis of 20 cohort studies

Addiction, EarlyView.
Abstract Background and aims Amid ongoing debate on whether low‐to‐moderate alcohol consumption reduces cardiovascular risk, studies examining the association between alcohol consumption and cognitive function have reported inconsistent results. To quantitatively assess this association, we conducted a dose–response meta‐analysis of cohort studies ...
Sooyeun Choi, Youjin Je
wiley   +1 more source

METTL14 inhibits atherogenesis by epigenetically activating PPAR-α/γ transcription and fatty acid oxidation in VSMCs. [PDF]

Cardiovasc Res
Cui L, Ho CK, Liang P, Gao W, Liu J, Tian XY, Wong R, Zhou B, Lui KO.   +8 more
europepmc   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

Acta Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina, Most Champa Begum, Xuan Tung Trinh, Turkuler Özgumus, Mikael Åkerlund, Peter Nilsson, Leticia Maria Spindola, Valeriya Lyssenko   +7 more
wiley   +1 more source

Comorbidity sequence, sex, and APOE-genotype forecast Alzheimer's disease diagnosis. [PDF]

Front Med (Lausanne)
Merlini S, Gatta R, Orini S, Basharat A, Farooq M, Brinton RD, Vitali F.   +6 more
europepmc   +1 more source

Data‐driven thresholds for standardized classification of severe Alzheimer's disease neuropathology using digital neuropathology

Brain Pathology, EarlyView.
We generated digital pathologic algorithms (AI‐based modules that can be freely shared) to: optimize the sampling (ROI) for diagnosis of ADNC‐related tau pathology; compare/transition between Aperio and HALO platforms; and rationalize severe Braak NFT staging, so that all Braak‐VI cases had dementia, and all Braak‐V cases had MCI or dementia.
Ryan K. Shahidehpour, Allison M. Neltner, Mitchell A. Klusty, Cole Corbett, Angelique D. Gonzalez, David A. Gutman, David W. Fardo, Adam D. Bachstetter, Cody Bumgardner, Margaret E. Flanagan, Peter T. Nelson   +10 more
wiley   +1 more source

APOE ε2/ε3 is associated with multi-layered protection against prostate cancer in Chinese men. [PDF]

World J Urol
Wang K, Zhang S, Chen M, Duan X, Xie Y, Yang X, Zhong Y, Yu P, Yang M, Wei Z, Tao Z, Liu W.   +11 more
europepmc   +1 more source

'SU' AND 'SUBASHIRA' OF ROOFED MUD-WALL

Journal of Architecture and Planning (Transactions of AIJ), 2006
HAYAMI, Yohei, SHINKAWA, Tatsuhiro, TSUCHIMOTO, Toshikazu   +2 more
openaire   +1 more source

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, EarlyView.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

Effects of age and APOE ϵ4 genotype on the relationship between pulse pressure and executive function in older adults without dementia. [PDF]

J Int Neuropsychol Soc
Quiring ML, Edwards L, Bangen KJ, Ho EH, Carlsson CM, Galasko D, Weintraub S, Gershon R, Salmon DP.   +8 more
europepmc   +1 more source