Results 21 to 30 of about 174,900 (290)
Alzheimer disease genetic risk factor APOE e4, and cognitive abilities in 111,739 UK Biobank participants [PDF]
, 2016 Background: the apolipoprotein (APOE) e4 locus is a genetic risk factor for dementia. Carriers of the e4 allele may be more vulnerable to conditions that are independent risk factors for cognitive decline, such as cardiometabolic diseases.
Anderson, Jana +14 more
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Pharmacogenomics and Personalized Medicine, 2022 Zhifu Xiao,1,* Haixia Zhao2,* 1Department of Thyroid Surgery, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China; 2Central Lab, General Hospital of Taiyuan Iron and Steel Group, Taiyuan, Shanxi, 030003 ...
Xiao Z, Zhao H
doaj
Independent associations of TOMM40 and APOE variants with body mass index [PDF]
, 2019 The TOMM40-APOE variants are known for their strong, antagonistic associations with Alzheimer's disease and body weight. While a stronger role of the APOE than TOMM40 variants in Alzheimer's disease was suggested, comparative contribution of the TOMM40 ...
Arbeev, Konstantin G +10 more
core +2 more sources
Атеросклероз, 2018 Aim: to form a panel of genetic markers for analyzing the risk of long-term adverse prognosis of cardiovascular diseases in Russia population. Material and methods.
E. V. Shakhtshneider +7 more
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The Suggestive Effect of Apo A, Apo B, and Apo A/Apo B on Erectile Dysfunction [PDF]
The Journal of Sexual Medicine, 2021 ABSTRACTBackgroundErectile dysfunction (ED) is closely related to coronary heart disease (CHD). Apolipoprotein (Apo) A1, Apo B, and Apo A/Apo B are known to be predictive factors for CHD. They are not yet a definite laboratory marker for the diagnosis of ED in cardiology. Therefore, we investigated the association between Apo A1, Apo B, and Apo A/Apo B,
Xiucheng, Li, Dongjie, Li
openaire +2 more sources
Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]
, 2016 Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht +13 more
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RNA-Seq Mouse Brain Regions Expression Data Analysis: Focus on ApoE Functional Network
Journal of Integrative Bioinformatics, 2017 ApoE expression status was proved to be a highly specific marker of energy metabolism rate in the brain. Along with its neighbor, Translocase of Outer Mitochondrial Membrane 40 kDa (TOMM40) which is involved in mitochondrial metabolism, the corresponding
Babenko Vladimir N. +2 more
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Microbiota and Alzheimer's disease: Toward new clinical approaches [PDF]
Medicinski PodmladakAlzheimer’s disease (AD) is now viewed as a systemic disorder in which genetics, the gut microbiome and immune dysregulation converge to accelerate amyloid-β (Aβ) and tau pathology. Genetic studies have identified 70 risk loci. The strongest AD risk loci
Đokić Jelena, Dinić Miroslav
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Comparison of Semantic and Episodic Memory BOLD fMRI Activation in Predicting Cognitive Decline in Older Adults [PDF]
, 2012 Previous studies suggest that task-activated functional magnetic resonance imaging (fMRI) can predict future cognitive decline among healthy older adults.
Butts, Alissa +11 more
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The role of the KIBRA and APOE genes in developing spatial abilities in humans
Вавиловский журнал генетики и селекции, 2022 In the contemporary high-tech society, spatial abilities predict individual life and professional success, especially in the STEM (Science, Technology, Engineering, and Mathematics) disciplines.
A. V. Kazantseva +8 more
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