Results 21 to 30 of about 174,340 (311)
APOE4 Status and cognitive function in middle-aged and elderly people
Balkan Journal of Medical Genetics, 2023 APOE is one of the prominent genes involved in the increased risk of developing Alzheimer’s disease, but its effect on cognition in patients who are not yet diagnosed with dementia or mild cognitive impairment is relatively understudied.
Pavel N.A. +4 more
doaj +1 more source
Independent associations of TOMM40 and APOE variants with body mass index [PDF]
, 2019 The TOMM40-APOE variants are known for their strong, antagonistic associations with Alzheimer's disease and body weight. While a stronger role of the APOE than TOMM40 variants in Alzheimer's disease was suggested, comparative contribution of the TOMM40 ...
Arbeev, Konstantin G +10 more
core +2 more sources
Pharmacogenomics and Personalized Medicine, 2022 Zhifu Xiao,1,* Haixia Zhao2,* 1Department of Thyroid Surgery, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China; 2Central Lab, General Hospital of Taiyuan Iron and Steel Group, Taiyuan, Shanxi, 030003 ...
Xiao Z, Zhao H
doaj
Brain APOE expression quantitative trait loci-based association study identified one susceptibility locus for Alzheimer\u27s disease by interacting with APOE epsilon 4 [PDF]
, 2018 Some studies have demonstrated interactions of AD-risk single nucleotide polymorphisms (SNPs) in non-APOE regions with APOE genotype. Nevertheless, no study reported interactions of expression quantitative trait locus (eQTL) for APOE with APOE genotype ...
Jiang, Shan +3 more
core +2 more sources
Атеросклероз, 2018 Aim: to form a panel of genetic markers for analyzing the risk of long-term adverse prognosis of cardiovascular diseases in Russia population. Material and methods.
E. V. Shakhtshneider +7 more
doaj +1 more source
The Suggestive Effect of Apo A, Apo B, and Apo A/Apo B on Erectile Dysfunction [PDF]
The Journal of Sexual Medicine, 2021 ABSTRACTBackgroundErectile dysfunction (ED) is closely related to coronary heart disease (CHD). Apolipoprotein (Apo) A1, Apo B, and Apo A/Apo B are known to be predictive factors for CHD. They are not yet a definite laboratory marker for the diagnosis of ED in cardiology. Therefore, we investigated the association between Apo A1, Apo B, and Apo A/Apo B,
Xiucheng, Li, Dongjie, Li
openaire +2 more sources
RNA-Seq Mouse Brain Regions Expression Data Analysis: Focus on ApoE Functional Network
Journal of Integrative Bioinformatics, 2017 ApoE expression status was proved to be a highly specific marker of energy metabolism rate in the brain. Along with its neighbor, Translocase of Outer Mitochondrial Membrane 40 kDa (TOMM40) which is involved in mitochondrial metabolism, the corresponding
Babenko Vladimir N. +2 more
doaj +1 more source
Microbiota and Alzheimer's disease: Toward new clinical approaches [PDF]
Medicinski PodmladakAlzheimer’s disease (AD) is now viewed as a systemic disorder in which genetics, the gut microbiome and immune dysregulation converge to accelerate amyloid-β (Aβ) and tau pathology. Genetic studies have identified 70 risk loci. The strongest AD risk loci
Đokić Jelena, Dinić Miroslav
doaj +1 more source
Comparison of Semantic and Episodic Memory BOLD fMRI Activation in Predicting Cognitive Decline in Older Adults [PDF]
, 2012 Previous studies suggest that task-activated functional magnetic resonance imaging (fMRI) can predict future cognitive decline among healthy older adults.
Butts, Alissa +11 more
core +2 more sources
Prediction of Cognitive Decline in Healthy Older Adults using fMRI [PDF]
, 2010 Few studies have examined the extent to which structural and functional MRI, alone and in combination with genetic biomarkers, can predict future cognitive decline in asymptomatic elders.
Antuono, Piero +11 more
core +2 more sources