Results 251 to 260 of about 121,312 (312)

A high‐fat, high‐sucrose diet exacerbates muscle and metabolic pathology and undermines glucocorticoid efficacy in dystrophin‐deficient mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat, high‐sucrose diet (HFHSD) exacerbated muscle and metabolic dysregulation in mdx mice while also altering the physiological response to prednisolone (Pred) In diaphragms of control diet (CD)‐fed mdx mice, prednisolone treatment improved muscle function and reduced fibrosis, inflammatory signalling, and mitochondrial ...
Morgan E. Vorwald   +5 more
wiley   +1 more source

Age-related increase in plasma p-tau217 in amyloid-beta-negative cognitively unimpaired individuals affects diagnostic interpretation. [PDF]

open access: yesAlzheimers Dement
Mammel AE   +11 more
europepmc   +1 more source

APOE4 negates the effects of ovarian hormones on cerebrovascular endothelial and mitochondrial function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We examined the interaction effect of ovarian hormones and APOE genotype on cerebrovascular and mitochondrial function. Our data revealed that APOEε3 mice that were ovariectomized exhibited impaired endothelial function and greater oxidative stress and inflammation compared to sham controls.
Mackenzie N. Kehmeier   +9 more
wiley   +1 more source

National Trends and Disparities in Cancer Mortality Among Individuals With Alzheimer's Disease and Related Dementias in the United States, 1999–2020

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT As population aging accelerates, the coexistence of cancer and Alzheimer's disease and related dementias (ADRD) is becoming increasingly common. While each condition independently contributes to mortality, national trends in cancer‐related deaths occurring alongside ADRD—and their demographic and geographic disparities—remain poorly defined ...
Aasim Ali   +14 more
wiley   +1 more source

Influence of Cardiometabolic and Alzheimer Disease Genetics on Cognitive-Related Outcomes in a Diverse Population. [PDF]

open access: yesNeurology
Kim D   +14 more
europepmc   +1 more source

Yin Yang 1 Specifically Supports the Development of Olig2 Positive Cerebellar Astrocytes

open access: yesGlia, Volume 74, Issue 8, August 2026.
Cerebellar Olig2 positive astrocytes are most abundant in the cerebellar nuclei. Cerebellar astrocytes expressing Olig2 have unique gene expression profiles. Yin Yang 1 specifically supports the development of astrocytes expressing Olig2. Deletion of YY1 during development increases numbers of astrocytes expressing Olig2 but hinders their ...
Masoumeh Zarei‐Kheirabadi   +9 more
wiley   +1 more source

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