Results 161 to 170 of about 135,666 (308)

'Collaborative' and 'Democratic' Professionalisms : Alternatives to 'Traditional' and 'Managerialist' Approaches to Teacher Autonomy?

Educational Studies in Japan, 2006
WHITTY, Geoff, WISBY, Emma
openaire   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Differential course of HIV-1 infection and apolipoprotein E polymorphism

Open Medicine, 2007
Corder Elizabeth, Galeazzi Luciano, Franceschi Claudio, Cossarizza Andrea, Paganelli Roberto, Pinti Marcello, Mussini Cristina, Borghi Vanni, Pinter Elena, Cristofaro Rita, Galeazzi Roberta, Perini Marino, Aiuti Fernando, Giunta Sergio   +13 more
doaj   +1 more source

'Career preference', 'transients' and 'converts': A study of social workers' retention in child protection and welfare

, 2011
Both domestically and internationally, retaining social workers in statutory child protection and welfare work has been identified as a problem. However, this issue appears to receive only modest attention from researchers. This paper reports on the findings of a study that examined the retention of ‘front line’ child protection and welfare social ...
openaire   +1 more source

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

What's in a name? The value of 'Entrepreneurs' compared to 'Self-Employed'...but what about 'Freelancing' or 'IPro'?

This paper is concerned with those individuals who do not fit easily or comfortably into traditional notions of employment. Variously described as 'self-employed', 'sole traders', 'own account workers,' 'freelancers,' 'independent contractors' - or more accurately, as independent professionals (IPros ...
openaire   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Genetic Resilience and Resistance in Alzheimer's Disease Diagnosis and Pathology

Annals of Neurology, EarlyView.
Objective Some individuals avoid Alzheimer's disease (AD) pathology as they age, or retain cognition despite substantial pathology, suggesting mechanisms of resistance or resilience to neurodegeneration. Educational attainment (EA) is associated with reduced risk of cognitive decline, although the underlying mechanisms remain unclear.
Ganna Leonenko, Kalliopi Mavromati, Lynne Hughes, Jonas S. Sundarakumar, Keeley Brookes, Kevin Morgan, Terry Quinn, Valentina Escott‐Price, the Alzheimer's Disease Neuroimaging Initiative   +8 more
wiley   +1 more source

Synthesis of the WXYZA'B'C'D'E'F' Ring of Maitotoxin

Journal of Synthetic Organic Chemistry, Japan, 2023
Umeno, Keitaro, Oishi, Tohru
openaire   +1 more source