Results 141 to 150 of about 135,666 (308)

''Η ηθικοπολιτική ύπαρξη των Μ.Κ.Ο.''

, 2022
Στην παρούσα έρευνα θα επιχειρήσουμε, με σημείο εκκίνησης την ιστορική αναδρομή στη σύσταση των Μη Κυβερνητικών Οργανώσεων, να θέσουμε ως αντικείμενο συζήτησης τη φιλοσοφική αντίληψη του ωφελιμισμού και της πρακτικής της εφαρμογής στις ΜΚΟ. Έτσι, αρχής γενομένης από την ανάλυση του τρόπου και των βασικών αρχών μέσω των οποίων οι εν λόγω οργανώσεις ...
openaire   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

Corpus-based analysis on the use of 'this' and 'it'

, 2018
Käesoleva bakalaurusetöö “Korpuseanalüüs asesõnade this ja it kasutamisest” teemaks on inglise keelt õppivate eestlaste asesõnade this ja it kasutamist. Analüüsiks oli võetud 2014. aasta Tartu Ülikooli õppijakeele korpus, mis koosnes 127-st tekstist, mis olid inglise keele ja kirjanduse õppe sisseastumiseksami kolmanda küsimuse vastused. Töö eesmärgiks
openaire   +1 more source

A Hybrid Hierarchical Framework for Quantifying Mechanical Markers in Atherosclerotic Disease Progression: A New Approach for Diagnosis and Risk Assessment

Advanced Science, EarlyView.
The mechanobiological basis of atherosclerotic progression and its contribution to spatial and temporal heterogeneity remain incompletely understood. Spatially resolved AFM measurements revealed that plaque formation and distinct regions (cap fibrosis, intimal fibrosis, and lipid‐rich core) exhibit heterogeneous elastic modulus and viscoelastic ...
Yidan Zhou, Zhuo Chang, Xianjun Wu, Sijie Wang, Yuzhi Zhang, Hao Zhang, Haoyu Xu, Ruining Peng, Zhe Wang, Huiyun Xu, Yu Liu, Guangkui Xu, Nu Zhang, Hui Yang   +13 more
wiley   +1 more source

''Wist U ervan?''

, 2007
De vuurwerkramp in Enschede, de ingestorte grachttrap in Utrecht, de moord op Theo van Gogh, de aanslagen van 11 september, de Bijlmerramp, de verspreiding van de SARS-pandemie, de Bijlmerramp ... Welke ramp er ook geschiedt, welke fouten er ook worden gemaakt, steevast wordt de vraag gesteld: waren de betrokken autoriteiten op de hoogte en zo ja, had ...
openaire   +1 more source

Detection of apoE and GFP proteins in control and transgenic (apoE-shRNA1) cloned pigs.

, 2013
(A) Immunoblots showing protein bands for apoE, GFP and β-actin in liver samples of control (lanes 1–3) and transgenic (4–9) cloned pigs. (B) Differences in apoE abundance between control and transgenic (apoE-shRNA1) liver samples was assessed by ...
Nayla El-Beirouthi (583874), Denyse Laurin (583879), Vilceu Bordignon (583873), Mario A. Martinez-Diaz (583877), Carine Schneider (583878), Luis B. Agellon (113612), Bernardo G. Gasperin (583875), David Zadworny (583880), Marcelo S. Albornoz (583876)   +8 more
core   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

Advanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li, Zhuoqiong Qiu, Xiaoyu Pan, Geyang Xu, Shanshan Peng, Ronghui Zhu, Qiuyang Luo, Xiaokai Fang, Xu Yao, Wei Li   +9 more
wiley   +1 more source

Van 'ancien' naar 'nouveau'

, 2000
"De redactie daagt u uit te reageren op dit stuk. In het volgende nummer zal de auteur de discussie aangaan en uw reacties onder de loep nemen, aan de hand waarvan tevens getracht zal worden een karakterisering te geven van een mogelijk 'nouveau regime'.
openaire   +1 more source

Cardiovascular Protection by ApoE and ApoE-HDL Linked to Suppression of ECM Gene Expression and Arterial Stiffening

, 2012
SummaryArterial stiffening is a risk factor for cardiovascular disease, but how arteries stay supple is unknown. Here, we show that apolipoprotein E (apoE) and apoE-containing high-density lipoprotein (apoE-HDL) maintain arterial elasticity by ...
Tina Xu, Fitzroy J. Byfield, Ellen Puré, Paola Castagnino, Michael C. Phillips, Daniel J. Rader, Shu-Lin Liu, James Monslow, Richard K. Assoian, Paul A. Janmey, Yong Ho Bae, Sissel Lund-Katz, Shilpa Rao, Elizabeth A. Hawthorne, Devashish Kothapalli   +14 more
core   +1 more source

Targeting Macrophage‐Mediated Lymphatic Immunosuppression to Prevent Tumor Recurrence After Microwave Ablation

Advanced Science, EarlyView.
Incomplete microwave ablation induces animmunosuppressive microenvironment in tumor‐draining lymph nodes. An albumin‐based lipoprotein nanosystem enables coordinated delivery of immunomodulators to tumor‐draining lymph nodes and residual tumors, reverses post‐ablation immunosuppression, suppresses residual tumor growth, and promotes durable antitumor ...
Xuexia Shan, Yuting Shen, Xiaodong Hou, Fengshan Jin, Shaoyue Li, Weichen Xu, Weiwei Ren, Xiaowan Bo, Qiuyan Li, Shuo Liu, Weifan Hao, Chengzhong Peng, Huixiong Xu, Liping Sun, Wenwen Yue   +14 more
wiley   +1 more source