Results 41 to 50 of about 277,563 (295)

Dyslipidemia and its relationship with chronic non-communicable diseases (according to the MERIDIAN-RO study)

Медицинский совет, 2015
MERIDIAN-RO, a prospective cohort cross-sectional study with retrospective component, aimed to evaluate the incidence of lipid metabolism disorders in the Ryazan region and their relationship with chronic non-communicable diseases. In 2011, 1,622 people (
E. V. Filippov, Y. A. Balanova
doaj   +1 more source

High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation [PDF]

, 2018
Recent evidence suggests that oxidative stress can play a role in the pathogenesis and the progression of prostate cancer (PCa). Reactive oxygen species (ROS) generation is higher in PCa cells compared to normal prostate epithelial cells and this ...
Botta, Margherita, Calabresi, Laura, Ferri, Nicola, Franceschini, Guido, Giorgio, Eleonora, Gomaraschi, Monica, Macchi, Chiara, Magni, Paolo, Ruscica, Massimiliano   +8 more
core   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Lipoprotein(a), a Lethal Player in Calcific Aortic Valve Disease

Frontiers in Cell and Developmental Biology, 2022
Calcified aortic valve disease (CAVD) is the most common valvular cardiovascular disease with increasing incidence and mortality. The primary treatment for CAVD is surgical or transcatheter aortic valve replacement and there remains a lack of effective ...
Jiahui Hu, Jiahui Hu, Jiahui Hu, Jiahui Hu, Hao Lei, Hao Lei, Hao Lei, Hao Lei, Leiling Liu, Leiling Liu, Leiling Liu, Leiling Liu, Danyan Xu, Danyan Xu, Danyan Xu, Danyan Xu   +15 more
doaj   +1 more source

Estimating the level of carbamoylated plasma non-high-density lipoproteins using infrared spectroscopy [PDF]

, 2019
Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In this
De Baene, Linde, De Bruyne, Sander, Delanghe, Joris, Delanghe, Sigurd, Speeckaert, Marijn, Van Biesen, Wim   +5 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Cellular cholesterol efflux in heterozygotes for Tangier disease is markedly reduced and correlates with high density lipoprotein cholesterol concentration and particle size

Journal of Lipid Research, 2000
Tangier disease (TD), caused by mutations in the ATP-binding cassette 1 (ABC-1) gene, is a rare genetic disorder characterized by severe deficiency of high density lipoproteins (HDL) in the plasma, hypercatabolism of HDL, and defective apolipoprotein ...
Margaret E. Brousseau, Gretchen P. Eberhart, Josée Dupuis, Bela F. Asztalos, Allison L. Goldkamp, Ernst J. Schaefer, Mason W. Freeman   +6 more
doaj   +1 more source

Agarose gel serum protein electrophoresis in cats with and without lymphoma and preliminary results of tandem mass fingerprinting analysis [PDF]

, 2011
<b>Background</b>: Serum electrophoretic profiles in cats are poorly characterized with respect to the protein components of the globulin fractions, and interpretation of the electrophoretograms has routinely been done in ignorance of the ...
Baker, Bence, Bing, Ceron, Cerón, Choi-Miura, Correa, Corzo, Dust, Eckersall, Furukawa, Giordano, González-Ramón, Hahn, Hofmann-Lehmann, Jeppsson, Keay, Kristensen, Lampreave, Laurell, MacEwen, McGrotty, Merlo, Moore, Nielsen, Ogilvie, Paltrinieri, Paltrinieri, Prenni, Roman, Saguchi, Selting, Sparkes, Stockham, Vail, Vavricka, Wiechselbaum   +36 more
core   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo

eLife, 2016
Apolipoprotein A1 (apoA1) is the major protein component of high-density lipoprotein (HDL) and has well documented anti-inflammatory properties. To better understand the cellular and molecular basis of the anti-inflammatory actions of apoA1, we explored ...
Asif J Iqbal, Tessa J Barrett, Lewis Taylor, Eileen McNeill, Arun Manmadhan, Carlota Recio, Alfredo Carmineri, Maximillian H Brodermann, Gemma E White, Dianne Cooper, Joseph A DiDonato, Maryam Zamanian-Daryoush, Stanley L Hazen, Keith M Channon, David R Greaves, Edward A Fisher   +15 more
doaj   +1 more source