CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li +8 more
wiley +1 more source
High Score of ELST-Blue in Endoscopic Ultrasonography Strain Elastography May Provide a High Risk Group of Early Chronic Pancreatitis with the Reduction of Apolipoprotein A2-i Index. [PDF]
Nakamura K +17 more
europepmc +1 more source
Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation. [PDF]
Lu J +7 more
europepmc +1 more source
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I. [PDF]
Liu X +15 more
europepmc +1 more source
The role of C-terminal ionic residues in self-association of apolipoprotein A-I. [PDF]
Burdick JP +3 more
europepmc +1 more source
Epigenetic Effectiveness of Complete Carcinogens: Specific Interactions of Polycyclic Aromatic Hydrocarbons and Aminoazo Dyes with Cholesterol and Apolipoprotein A-I [PDF]
Bodo Contag
openalex +1 more source
Abstract Background Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a cytosine‐adenine‐guanine (CAG) repeat expansion in the huntingtin gene. The disease exhibits sex‐related differences in symptomatology and disease progression, but the effect on brain structural biomarkers and the interaction between sex and CAG‐age ...
Jingwen Yao +10 more
wiley +1 more source

