Results 231 to 240 of about 97,019 (266)
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Apolipoprotein A-IMilano and Apolipoprotein A-IParis Exhibit an Antioxidant Activity Distinct from That of Wild-Type Apolipoprotein A-I

Biochemistry, 2002
Apolipoprotein A-I(Milano) (apoA-I(Milano)) and apoA-I(Paris) are rare cysteine variants of apoA-I that produce a HDL deficiency in the absence of cardiovascular disease in humans. This paradox provides the basis for the hypothesis that the cysteine variants possess a beneficial activity not associated with wild-type apoA-I (apoA-I(WT)). In this study,
John K, Bielicki, Michael N, Oda
openaire   +3 more sources

Pharmacology of apolipoprotein A-l

Current Opinion in Lipidology, 1997
The role of HDL and its main protein component the apolipoprotein A-I as being antiatherogenic is well established. Experimental data give support for the involvement of at least three different types of mechanism: (1) the reverse cholesterol transport, (2) anti-inflammatory mechanisms and (3) antithrombotic mechanisms.
openaire   +2 more sources

Apolipoprotein A-I and risk for cardiovascular diseases

Current Atherosclerosis Reports, 2006
Increased concentrations of high-density lipoprotein (HDL) cholesterol have been closely associated with decreased risk of future cardiovascular disease. This protective effect of HDL has been mainly attributed to its involvement in reverse cholesterol transport.
Natalie, Khuseyinova, Wolfgang, Koenig
openaire   +2 more sources

Synthesis and secretion of apolipoprotein A-I

Biochemical Society Transactions, 1993
CALANDRA BUONAURA, Sebastiano   +1 more
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Repeated helical pattern in apolipoprotein-A-I

Nature, 1977
THE binding of lipids into globules by the serum lipid-binding proteins depends on the unique structures of these proteins. Many have a high α helix content1–4 which is enhanced by the binding of lipid, and their amino acid sequences5–8 suggest that the helices are often ‘amphipathic’ with a long hydrophobic face buried in the lipid surface9,10 and an ...
openaire   +2 more sources

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

Lipids and Lipid Metabolism, 1987
J K Boyles   +2 more
exaly  

Apolipoprotein E in Alzheimer's Disease: An Update

Annual Review of Neuroscience, 2014
Jintai Yu, John Hardy, Lan Tan
exaly  

[Lipid-poor apolipoprotein A-I, glycated apolipoprotein A-I].

Nihon rinsho. Japanese journal of clinical medicine, 2005
Satoshi, Maeda   +2 more
openaire   +1 more source

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