Results 91 to 100 of about 803,874 (212)

Metabolism of C-apolipoproteins: kinetics of C-II, C-III1 and C-III2, and VLDL-apolipoprotein B in normal and hyperlipoproteinemic subjects.

open access: yesJournal of Lipid Research, 1981
The turnover and metabolism of the individual C apolipoproteins (C-II, C-III1, and C-III2) were studied following the injection of 125I-labeled VLDL into 15 normal and hyperlipoproteinemic subjects. The C apolipoproteins from very low density lipoprotein
M W Huff   +4 more
doaj   +1 more source

Transcriptional downregulation of agr expression in Staphylococcus aureus during growth in human serum can be overcome by constitutively active mutant forms of the sensor kinase AgrC [PDF]

open access: yes, 2013
The temporal and cell density-dependent regulation of expression of virtually all the Staphylococcus aureus virulon is under the control of the agr (accessory gene regulatory) operon.
Edwards, AM   +2 more
core   +1 more source

Altered High Density Lipoprotein Composition in Behavioral Variant Frontotemporal Dementia

open access: yesFrontiers in Neuroscience, 2018
Frontotemporal dementia (FTD) is a common cause of early onset dementia with behavioral variant FTD (bvFTD) being the most common form. bvFTD is characterized clinically by behavioral and personality changes, eating abnormalities, and pathologically, by ...
Woojin Scott Kim   +17 more
doaj   +1 more source

Overexpression of Human Apolipoprotein A-II in Mice Induces Hypertriglyceridemia Due to Defective Very Low Density Lipoprotein Hydrolysis*

open access: yesJournal of Biological Chemistry, 1999
Two lines of transgenic mice, hAIItg-δ and hAIItg-λ, expressing human apolipoprotein (apo)A-II at 2 and 4 times the normal concentration, respectively, displayed on standard chow postprandial chylomicronemia, large quantities of very low density ...
E. Boisfer   +12 more
semanticscholar   +1 more source

Characterization and measurement of human apolipoprotein A-II by radioimmunoassay

open access: yesJournal of Lipid Research, 1980
The development of a radioimmunoassay for apolipoprotein A-II (apo A-II) is described. Initial studies revealed a lack of immunological identity between purified apo A-II used as the standard and serum or HDL. Extensive testing of different buffers, standards, antisera, tracers, utilization of a detergent, and heating of sera failed to resolve the ...
R B Goldberg   +5 more
openaire   +3 more sources

Isolation and characterization of an apoA-II-containing lipoprotein (LP-A-II:B complex) from plasma very low density lipoproteins of patients with Tangier disease and type V hyperlipoproteinemia.

open access: yesJournal of Lipid Research, 1991
Previous studies have shown that very low density lipoproteins (VLDL) from patients with Tangier disease are less effective as a substrate for human milk lipoprotein lipase (LPL) than VLDL from normal controls as assessed by measuring the first order ...
P Alaupovic   +6 more
doaj   +1 more source

Isoproteins of human apolipoprotein A-II: isolation and characterization.

open access: yesJournal of Lipid Research, 1983
In human serum, polymorphism of apoA-II predominantly in HDL3 could be demonstrated. HDL3-apoA-II was composed of four isoproteins, each with a molecular weight of 8600 (reduced form) and identical immunological properties. The isoproteins are designated
G Schmitz   +3 more
doaj   +1 more source

Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. [PDF]

open access: yes, 2018
Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell (HSPC) maintenance.
Han, Tianxu   +10 more
core   +2 more sources

Depletion in LpA-I:A-II particles enhances HDL-mediated endothelial protection in familial LCAT deficiency[S]

open access: yesJournal of Lipid Research, 2017
The aim of this study was to evaluate the vasoprotective effects of HDL isolated from carriers of LCAT deficiency, which are characterized by a selective depletion of LpA-I:A-II particles and predominance of preβ migrating HDL.
Monica Gomaraschi   +13 more
doaj   +1 more source

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