Results 41 to 50 of about 803,874 (212)

Apolipoprotein Profiles in Very Preterm and Term‐Born Preschool Children

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Little is known about plasma apolipoprotein profiles in very preterm‐born and term‐born preschool children compared with the adult population.
Anna Posod, Raimund Pechlaner, Xiaoke Yin, Sean Anthony Burnap, Sophia Julia Kiechl, Johann Willeit, Joseph L. Witztum, Manuel Mayr, Stefan Kiechl, Ursula Kiechl‐Kohlendorfer   +9 more
doaj   +1 more source

Apolipoprotein A-II [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2013
Apolipoprotein (apo) A-II is the second most abundant protein on high-density lipoprotein (HDL), accounting for ≈20% of total HDL protein.1 Like apo A-I, the most abundant HDL protein, it contains a tandem array of amphipathic helices. It is considered an exchangeable apolipoprotein because it can dissociate from lipoproteins, although it has greater ...
openaire   +2 more sources

High postprandial triglyceridemia in patients with type 2 diabetes and microalbuminuria

Journal of Lipid Research, 2007
Microalbuminuria (MA) is an independent risk factor for atherosclerosis in patients with type 2 diabetes mellitus (T2DM). Postprandial lipemia is also associated with excess cardiovascular risk.
Nicholas Tentolouris, Andreas Stylianou, Evangelia Lourida, Despoina Perrea, Despoina Kyriaki, Eleni C. Papavasiliou, Alexandros D. Tselepis, Nicholas Katsilambros   +7 more
doaj   +1 more source

Oral Apolipoprotein A-I Mimetic D-4F Lowers HDL-Inflammatory Index in High-Risk Patients: A First-in-Human Multiple-Dose, Randomized Controlled Trial. [PDF]

, 2017
A single dose of the apolipoprotein (apo)A-I mimetic peptide D-4F rendered high-density lipoprotein (HDL) less inflammatory, motivating the first multiple-dose study. We aimed to assess safety/tolerability, pharmacokinetics, and pharmacodynamics of daily,
Bloedon, LeAnne T., Duffy, Danielle, Dunbar, Richard L., Fogelman, Alan M., Movva, Rajesh, Navab, Mohamad, Norris, Robert B., Rader, Daniel J.   +7 more
core   +2 more sources

High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation [PDF]

, 2018
Recent evidence suggests that oxidative stress can play a role in the pathogenesis and the progression of prostate cancer (PCa). Reactive oxygen species (ROS) generation is higher in PCa cells compared to normal prostate epithelial cells and this ...
Botta, Margherita, Calabresi, Laura, Ferri, Nicola, Franceschini, Guido, Giorgio, Eleonora, Gomaraschi, Monica, Macchi, Chiara, Magni, Paolo, Ruscica, Massimiliano   +8 more
core   +2 more sources

Apolipoprotein A-II Influences Apolipoprotein E-Linked Cardiovascular Disease Risk in Women with High Levels of HDL Cholesterol and C-Reactive Protein

PLoS ONE, 2012
Background In a previous report by our group, high levels of apolipoprotein E (apoE) were demonstrated to be associated with risk of incident cardiovascular disease in women with high levels of C-reactive protein (CRP) in the setting of both low ...
J. Corsetti, S. Bakker, C. Sparks, R. Dullaart   +3 more
semanticscholar   +1 more source

Effects of peroxisome proliferator-activated receptor α/δ agonists on HDL-cholesterol in vervet monkeys

Journal of Lipid Research, 2005
The objective of this study was to demonstrate the efficacy of a novel peroxisome proliferator-activated receptor (PPAR) agonist and known PPARα and PPARδ agonists to increase HDL-cholesterol (HDL-C) in the St.
Jeanne M. Wallace, Margrit Schwarz, Peter Coward, Jonathan Houze, Janet K. Sawyer, Kathryn L. Kelley, Anne Chai, Lawrence L. Rudel   +7 more
doaj   +1 more source

Apolipoprotein A-II-mediated Conformational Changes of Apolipoprotein A-I in Discoidal High Density Lipoproteins [PDF]

Journal of Biological Chemistry, 2012
It is well accepted that HDL has the ability to reduce risks for several chronic diseases. To gain insights into the functional properties of HDL, it is critical to understand the HDL structure in detail. To understand interactions between the two major apolipoproteins (apos), apoA-I and apoA-II in HDL, we generated highly defined benchmark discoidal ...
Kekulawalage, Gauthamadasa, Nataraja Sarma, Vaitinadin, James L, Dressman, Stephen, Macha, Reyn, Homan, Kenneth D, Greis, R A Gangani D, Silva   +6 more
openaire   +2 more sources

Differential tissue-specific expression of human apoA-I and apoA-II

Journal of Lipid Research, 1991
To evaluate the sources of high density lipoprotein (HDL) particles containing only apolipoprotein A-I (apoA-I), the synthesis of apoA-I and apolipoprotein A-II (apoA-II) was examined in human liver and small intestine as well as the human intestinally ...
TL Eggerman, JM Hoeg, MS Meng, A Tombragel, D Bojanovski, HB Brewer, Jr   +5 more
doaj   +1 more source

Apolipoprotein A-II Inhibits High Density Lipoprotein Remodeling and Lipid-poor Apolipoprotein A-I Formation [PDF]

Journal of Biological Chemistry, 2003
The high density lipoproteins (HDL) in human plasma are classified on the basis of apolipoprotein composition into those containing apolipoprotein (apo) A-I but not apoA-II, (A-I)HDL, and those containing both apoA-I and apoA-II, (A-I/A-II)HDL. Cholesteryl ester transfer protein (CETP) transfers core lipids between HDL and other lipoproteins.
Rye, Kerry-Anne, Wee, K., Curtiss, Linda K., Bonnet, David J., Barter, Philip John   +4 more
openaire   +2 more sources