Results 81 to 90 of about 280,160 (254)
Ibrain, EarlyView.Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley +1 more source
Asian Journal of Medical Sciences, 2016 Background: Obesity and hyperlipidemia are considered to be risk factor for cardiovascular diseases. Many patients who develop coronary artery disease (CAD) are non obese and have normal lipoprotein cholesterol.
Sunita Mahto
doaj +1 more source
PLoS ONE, 2021 Background and aimsThe Apo B/A1 ratio is a major factor that predicts future cardiovascular outcomes. However, it is unclear whether the apolipoprotein B (Apo B)/apolipoprotein A1 (Apo A1) is a better predictor of future outcome than the total ...
Hae Won Jung +2 more
doaj +1 more source
iMetaOmics, EarlyView.First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang +9 more
wiley +1 more source
Lipid Profile Alterations Across Coronary Heart Disease, Metabolic Syndrome, and Nephrotic Syndrome
Journal of Clinical Laboratory Analysis, EarlyView.CHD, MetS, and NS exhibit distinct dyslipidemia patterns. TC, TG, ApoB, ApoE, and sdLDL‐C are key markers for disease differentiation. This study found that elevated TC and sdLDL‐C were key pathogenic factors in CHD. In contrast, TG and ApoB played significant roles in the pathogenesis of MetS.
Shudong Tan +3 more
wiley +1 more source
Placental secretion of apolipoprotein A1 and E: the anti-atherogenic impact of the placenta
Scientific Reports, 2019 High levels of atherogenic lipids in pregnancy are associated with health complications for the mother, the fetus and the newborn. As endocrine secretory tissue, the human placenta releases apolipoproteins (apos), particularly apoA1 and apoE.
H. Melhem +9 more
semanticscholar +1 more source
Apolipoprotein A1/C3/A5 haplotypes and serum lipid levels [PDF]
Heart, 2011 Background and aims Single nucleotide polymorphisms (SNPs) at the apolipoprotein (Apo) A1/C3/A4/A5 gene cluster have been examined in relation to lipid metabolism and cardiovascular disease risk. However, the previous findings are inconsistent. The present study was undertaken to detect the association between ApoA1/
Li Yi-Yang, Yin Rui-Xing, Lai Chao-Qiang
openaire +4 more sources
Lipids, EarlyView.ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao +5 more
wiley +1 more source
New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects
Turkish Journal of Hematology, 2010 OBJECTIVE: We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione, nitrite, aggregation response, and expressions of P-selectin, fibrinogen, apolipoprotein A1 ...
Derya Özsavcı +5 more
doaj +3 more sources
Lipids, EarlyView.ABSTRACT Cardiovascular diseases (CVD) are a leading cause of global mortality, with dyslipidemia playing a central role in their pathogenesis. The influence of alcohol consumption on lipid profiles, particularly high‐density lipoprotein cholesterol (HDL‐c), in relation to obesity status remains insufficiently explored.
Larissa Esthefani Barros Cirino +6 more
wiley +1 more source