Results 141 to 150 of about 92,925 (293)

Prognosis in Parkinson's Disease: An Individual Patient Data Meta‐Analysis of Six European Incidence Cohorts

Movement Disorders, EarlyView.
Abstract Background An accurate understanding of prognosis in Parkinson's disease (PD) is important for patient information provision, personalized treatment, and clinical trial design, but most previous research has been biased towards younger, healthier patients.
Angus D. Macleod, David J. McLernon, Marta Camacho, Caroline H. Williams‐Gray, Rachael A. Lawson, Alison J. Yarnall, David Bäckström, Lars Forsgren, Jodi Maple‐Grødem, Guido Alves, Ole‐Bjørn Tysnes, Carl E. Counsell, Parkinson's Incidence Cohorts Collaboration, Thomas Foltynie, Sarah L. Mason, Ruwani Wijeyekoon, Jonathan Evans, David P. Breen, Gemma Cummins, Krista Farrell, Kirsten Scott, Tom Stoker, Julia Greenland, Natalie Valle Guzman, Lucy Collins, Simon Stott, Jan Linder, Mona Edström, Jörgen Andersson, Linda Eriksson, Gun‐Marie Hariz, Magdalena Domellöf, Michaela Dreetz Gjerstad, Kenn Freddy Pedersen, Elin Bjelland Forsaa, Veslemøy Hamre Frantzen, Anita Laugaland, Johannes Lange, Karen Simonsen, Eldbjørg Fiske, Ingvild Dalen, Bernd Müller, Geir Olve Skeie, Marit Renså, Wenche Telstad, Aliaksei Labusau, Jane Kastet, Ineke HogenEsch, Marianne Kjerandsen, Liv Kari Håland, Karen Herlofson, Solgunn Ongre, Siri Bruun, David Burn, Lynn Rochester, Gordon W. Duncan, Tien K. Khoo, Kate S. M. Taylor, Robert Caslake, David J. M. McGhee, Diane Swallow, Joanne Gordon, Clare Harris, Ann Hayman, Nicola Johannesson, Hazel Forbes, Valerie Angus, Alasdair Finlayson, David Dawson, Katie Wilde, David Ritchie, Artur Wozniak, Adrian Martin   +72 more
wiley   +1 more source

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo, Per Borghammer, Inas Elsayed, Jennifer G. Goldman, Yue Huang, Katja Lohmann, Per Svenningsson, Lorraine V. Kalia, Daniela Berg, Jeffrey H. Kordower, the MDS Scientific Issues Committee   +10 more
wiley   +1 more source

Pemetaan gen apolipoprotein B-100 manusia dengan menggunakan primer 1,2,4, dan 6 pada mahasiswa PSPD UINSH Jakarta

Latar belakang. Penentuan sekuens gen apolipoprotein B-100 dapat digunakan sebagai madia untuk mengidentifikasi, mendiagnosis, dan mengembangkan pengobatan penyakit genetik, salah satunya hiperkolesterolemia familial.
HARITSAH
core  

Depletion of microglial compensation in glial network: Disease‐associated response dynamics in the revised amyloid hypothesis

Neuroprotection, EarlyView.
The critical transition from amyloid pathology to irreversible neuronal loss in Alzheimer's disease hinges on the microglial response. This review aims to systematize the patterns of how microglia react within the glial context. Abstract Microglia mount coordinated, stage‐dependent compensatory programs in response to early amyloid β (Aβ) accumulation ...
Songtao Lei, Zixuan Huang, Wen Wang, Yan Meng   +3 more
wiley   +1 more source

Structural changes induced by acidic pH in human apolipoprotein B-100. [PDF]

Sci Rep, 2016
Fernández-Higuero JA, Benito-Vicente A, Etxebarria A, Milicua JC, Ostolaza H, Arrondo JL, Martín C.   +6 more
europepmc   +1 more source

KORELASI KADAR APOLIPOPROTEIN B-100 DENGAN STENOSIS ARTERI KORONER PADA SINDROM KORONER AKUT [PDF]

, 2019
Latar Belakang: Sindrom koroner akut (SKA) terjadi akibat proses aterosklerosis yang menyebabkan penyempitan lumen pembuluh darah koroner (stenosis arteri koroner).
Cici, Julia Sri Dewi
core  

Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease

Neuroprotection, EarlyView.
In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong, Andrew Octavian Sasmita, Rhun Yian Koh, Anna Pick Kiong Ling   +3 more
wiley   +1 more source

In vitro oxidative footprinting provides insight into apolipoprotein B-100 structure in low-density lipoprotein. [PDF]

Proteomics, 2014
Chakraborty S, Cai Y, Tarr MA.
europepmc   +1 more source

Weight Change Between Pregnancies and Mortality Over 50 Years of Follow‐Up

Obesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the link between postpartum weight retention (PPWR) and long‐term mortality. Methods In this secondary analysis of 8165 women with ≥ 2 pregnancies in the Collaborative Perinatal Project (CPP), U.S., 1959–1966, with vital status follow‐up through 2016, we used interconception weight change (ICWC) and ...
Yajnaseni Chakraborti, Sunni L. Mumford, Edwina H. Yeung, Katherine L. Grantz, Pauline Mendola, James L. Mills, Ellen C. Caniglia, Colleen M. Brensinger, Cuilin Zhang, Enrique F. Schisterman, Stefanie N. Hinkle   +10 more
wiley   +1 more source

A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease. [PDF]

J Infect Dis, 2015
Crowley JT, Drouin EE, Pianta A, Strle K, Wang Q, Costello CE, Steere AC.   +6 more
europepmc   +1 more source