Liver Steatosis in Induced Hepatocytes From Carriers of Spinal Muscular Atrophy
ABSTRACT Introduction/Aims Although classically characterized as a motor neuron disease, spinal muscular atrophy (SMA) is increasingly recognized as a multisystem disorder. We previously showed hepatocyte‐intrinsic steatosis in SMA, raising the question of whether SMA carriers, who are typically asymptomatic, may also exhibit subclinical hepatic ...
Lingyu Sun +15 more
wiley +1 more source
Substitution of dietary ω-6 polyunsaturated fatty acids for saturated fatty acids decreases LDL apolipoprotein B-100 production rate in men with dyslipidemia associated with insulin resistance: a randomized controlled trial. [PDF]
Drouin-Chartier JP +5 more
europepmc +1 more source
Differential Proteomics of Large Extracellular Vesicles in Ovarian Cancer
ABSTRACT Diverse extracellular vesicles (EVs) are present in all body fluids; however, knowledge of large EVs (lEVs) remains limited. Molecular EV profiles vary depending on EV size and the physiological circulatory system, even within the same patient. In this study, we aimed to characterize the proteomic profile of IEVs in ovarian cancer patients and
Kazuhiro Suzuki +6 more
wiley +1 more source
Cultured cells of the blood-brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment. [PDF]
Lénárt N +13 more
europepmc +1 more source
Modular Structure of Solubilized Human Apolipoprotein B-100 [PDF]
Alexander Johs +5 more
openaire +1 more source
Proteomics of Prostate Cancer Tissue Small Extracellular Vesicles Reveal Alteration of Metabolism
ABSTRACT Prostate cancer (PCa) is a leading male malignancy worldwide, with metabolic reprogramming being a critical hallmark of its progression. Extracellular vesicles (EVs) derived from tissues directly reflect the tumor microenvironment, offering unique insights into cancer pathophysiology that are unattainable through cell line or biofluid‐derived ...
Lijuan Yu +4 more
wiley +1 more source
Identification of Major Histocompatibility Complex Class II Epitopes From Lyme Autoantigen Apolipoprotein B-100 and Borrelia burgdorferi Mcp4 in Murine Lyme Arthritis. [PDF]
Danner R +6 more
europepmc +1 more source
Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials. [PDF]
Santos RD +5 more
europepmc +1 more source

