Results 171 to 180 of about 92,925 (293)

Utilization of cognitive support in episodic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older

, 2004
Apolipoprotein E (APOE), vitamin B12, and folate were examined in relation to free recall among 167 community-based older adults. Cognitive support at encoding and retrieval was also taken into account.
Kivipelto, M, Wahlin, A, Bunce, D
core  

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

Substitution of dietary monounsaturated fatty acids from olive oil for saturated fatty acids from lard increases low-density lipoprotein apolipoprotein B-100 fractional catabolic rate in subjects with dyslipidemia associated with insulin resistance: a randomized controlled trial. [PDF]

Am J Clin Nutr
Desjardins LC, Brière F, Tremblay AJ, Rancourt-Bouchard M, Drouin-Chartier JP, Corbeil J, Lemelin V, Charest A, Schaefer EJ, Lamarche B, Couture P.   +10 more
europepmc   +1 more source

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

Journal of Internal Medicine, EarlyView.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca, Elias Björnson, Laura D'Erasmo, Alessia Di Costanzo, Simone Bini, Ilenia Minicocci, Daniele Tramontano, Stella Covino, Giuseppe Ciarlo, Manuela Lombardi, Sanni Söderlund, Niina Matikainen, Linda Andersson, Martin Adiels, Marja‐Riitta Taskinen, Chris J. Packard, Jan Borén   +16 more
wiley   +1 more source

Relationship of oxidized phospholipids on apolipoprotein B-100 to cardiovascular outcomes in patients treated with intensive versus moderate atorvastatin therapy: the TNT trial. [PDF]

J Am Coll Cardiol, 2015
Byun YS, Lee JH, Arsenault BJ, Yang X, Bao W, DeMicco D, Laskey R, Witztum JL, Tsimikas S, TNT Trial Investigators.   +9 more
europepmc   +1 more source

Evaluating School‐Based Obesity Prevention Interventions in 6‐ to 12‐Year‐Old Children: A Scoping Review of All Reported Outcomes and Expert Consultation

Obesity Reviews, EarlyView.
ABSTRACT Introduction This scoping review aims to identify all outcomes reported in school‐based obesity prevention interventions in childhood. It serves as an essential first step towards developing an internationally agreed‐upon Core Outcome Set (COS), which defines what should be measured in all school‐based childhood obesity prevention studies ...
Teatske M. Altenburg, Lotte W. de Vries, Iris J. Grooten, Janneke van 't Hooft, Arend W. van Deutekom, Tessa Roseboom, Erica van den Akker, Michael Duncan, Ulf Ekelund, John J. Reilly, Lisa Reilly, Annette Stafleu, Martyn Standage, Mai J. M. Chinapaw, Deirdre M. Harrington   +14 more
wiley   +1 more source

Retardation of atherosclerosis in immunocompetent apolipoprotein (apo) E-deficient mice followingliver-directed administration of a [E1-, E3-,polymerase-] adenovirus vector containing the elongation factor-1a promoter driving expression of human apoE cDNA

, 2005
Although gene transfer of human apolipoprotein E (apoE), a 34-kDa circulating glycoprotein, to the liver of apoEdeficient(apoE-/-) mice using recombinant adenoviral vectors (rAd) is antiatherogenic, its full therapeutic potentialhas yet to be realized ...
Stannard, AK, Amalfitano, A, Owen, JS, Dickson, G, Schepelmann, S, Graham, IR, Harris, JD   +6 more
core  

Sütçü sığırların periparturient dönem hastalıklarında serum apolipoprotein B-100 konsantrasyonları

, 2003
Çalışmada sütçü sığırların periparturient dönem hastalıklarında serum apolipoprotein B-100 konsantrasyonlarında değişim araştırıldı ve karaciğer fonksiyonu değerlendirildi.
Sevinç, Mutlu, Civelek, Turan
core  

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Human breast milk lipoproteins: A preliminary biochemical characterization

Experimental Physiology, EarlyView.
Abstract Human breast milk (BM) is an essential fluid for infant development, with a dynamic composition adapted to the infant's needs. It contains bioactive lipids like cholesterol, typically transported by lactosomes, extracellular vesicles, and milk fat globules. However, classic cholesterol‐carrying lipoproteins have not been described in BM.
Gabriela Arenas, Andrea Morales, Andrea Leiva, Susana Contreras‐Duarte   +3 more
wiley   +1 more source