Results 191 to 200 of about 145,356 (331)

Proteomic and Lipidomic Profiling of Immune Cell‐Derived Subpopulations of Extracellular Vesicles

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are heterogeneous and play important roles in intercellular communication, contributing to physiological and pathological processes. Since few markers currently exist to differentiate subtypes of EVs, this study aimed to determine proteomic and lipidomic differences among four EV subpopulations. Large and small EVs
Anna Lischnig   +6 more
wiley   +1 more source

Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in NIDDM [PDF]

open access: bronze, 1995
M. H. Cummings   +7 more
openalex   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

open access: yesSmall Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto   +12 more
wiley   +1 more source

Unilateral mastication‐induced memory deficits linked to disrupted hippocampal cholesterol metabolism in rats

open access: yesVIEW, EarlyView.
Unilateral mastication, a common oral habit, induces cognitive decline in rats by disrupting hippocampal cholesterol metabolism. It triggers astrocyte hyperplasia, enhances cholesterol synthesis, impairs transport/degradation, and reduces 24‐hydroxycholesterol (24‐OHC), ultimately damaging synaptic function.
Xiaoting Zhai   +9 more
wiley   +1 more source

Relationship of oxidized phospholipids on apolipoprotein B-100 to cardiovascular outcomes in patients treated with intensive versus moderate atorvastatin therapy: the TNT trial. [PDF]

open access: yesJ Am Coll Cardiol, 2015
Byun YS   +9 more
europepmc   +1 more source

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