Results 221 to 230 of about 145,356 (331)

Defective high‐density lipoprotein lipoprotection in type 2 diabetes during acute myocardial infarction is rescued by apolipoprotein M/sphingosine‐1‐phosphate loading

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt   +12 more
wiley   +1 more source

Long‐term effects of a multidomain intervention on cognitive function and metabolic control in older adults with type 2 diabetes and mild cognitive impairment: A 42‐month follow‐up of the J‐MIND‐Diabetes study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This study investigated the long‐term effects of a multidomain intervention on cognition and metabolic control in patients with type 2 diabetes and mild cognitive impairment (MCI). Materials and methods Outpatients aged 70–85 years were randomized to an 18‐month multidomain intervention (comprising metabolic/vascular risk management ...
Taiki Sugimoto   +16 more
wiley   +1 more source

Beyond PD‐1: Mechanisms of Resistance to Checkpoint Blockade in Classical Hodgkin Lymphoma and Next‐Generation Immune Strategies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT PD‐1 inhibitors have reshaped the treatment landscape of classical Hodgkin lymphoma, yet a substantial proportion of patients exhibit primary or acquired resistance driven by tumor‐intrinsic alterations, immunosuppressive microenvironmental signals, metabolic constraints, and EBV‐mediated modulation.
Santino Caserta   +12 more
wiley   +1 more source

Apolipoprotein B-100-containing lipoprotein metabolism in subjects with lipoprotein lipase gene mutations. [PDF]

open access: yesArterioscler Thromb Vasc Biol, 2012
Ooi EM   +9 more
europepmc   +1 more source

Intranasal Immunization With an Apolipoprotein B-100 Fusion Protein Induces Antigen-Specific Regulatory T Cells and Reduces Atherosclerosis

open access: green, 2010
Roland Klingenberg   +10 more
openalex   +1 more source

Alcohol consumption and risk of dementia: a systematic review and meta‐analysis

open access: yesInternal Medicine Journal, EarlyView.
Abstract To examine the relationship between alcohol intake and the risk of developing dementia, we conducted a comprehensive search of PubMed, Embase, Cochrane Library and Web of Science databases for relevant studies up to July 22, 2024. The quality of the original studies was appraised utilising the Newcastle‐Ottawa Scale (NOS).
Ren Zhang, Baitao Li, Yue Miao
wiley   +1 more source

APOE ε4 and Decline in Health and Financial Literacy in Advanced Age

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Health and financial literacy decline in aging, but it is unclear why. In this study, we hypothesized that older people who are carriers of the APOE ε4 allele exhibit a steeper decline in literacy over time. Methods Participants were 851 community‐dwelling older adults without dementia at analytic baseline (188 ε4 carriers and 663 ...
Christopher C. Stewart   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy