Translating the effect of dual lipid reduction with PCSK9 inhibitors on a mechanical vascular instrumental biomarker in familial hypercholesterolemia subjects. [PDF]
Bosco G +13 more
europepmc +1 more source
From platelets to particles: Optimizing extracellular vesicle isolation in a National Blood Centre
Abstract Background and Objectives Platelet‐derived extracellular vesicles (PEVs) are submicron, membrane‐bound particles released upon platelet activation, with a recognized role in haemostasis, inflammation and immunoregulation. PEVs remain insufficiently characterized in blood products.
Y. Chintala +5 more
wiley +1 more source
Patterns of lipid profile and genetic variations in South Asians. [PDF]
Rahmanian M.
europepmc +1 more source
Nutritional repletion of children with severe acute malnutrition does not affect VLDL apolipoprotein B-100 synthesis rate. [PDF]
Badaloo AV +3 more
europepmc +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Association of tubular injury with lipid metabolism: A Mendelian randomization study. [PDF]
Zhao K, Qian L, Ma X.
europepmc +1 more source
Enzyme-linked Immunosorbent Assays of Canine Apolipoproteins B-100 and A-I.
Kenjirou MIYOSHI +2 more
openalex +2 more sources
Abstract A mouse model of HIV‐associated atherosclerosis (Tg26+/−ApoE−/−) exhibited increased plaque area compared with the ApoE−/− mouse, linked to elevated indoleamine 2,3‐dioxygenase (IDO) activity. IDO catalyses the conversion of tryptophan (TRP) into kynurenine (KYN), measured by the KYN‐to‐TRP ratio.
Marcus V. S. Rangel +5 more
wiley +1 more source
Genetic Association of Lipids and Lipid-Lowering Drug Target Genes With Atopic Dermatitis: A Drug Target Mendelian Randomization Study. [PDF]
Luo M, Lin J, Zhuo Q, Lin L, Han Y.
europepmc +1 more source
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira +3 more
wiley +1 more source

