Results 261 to 270 of about 92,925 (293)

[Familial defective apolipoprotein B-100].

Ryoikibetsu shokogun shirizu, 1998
Abnormal interaction between low density lipoprotein receptors (LDLR) and their ligands, apolipoprotein E and B, causes decreased catabolism of lipoproteins which carry these apolipoproteins (VLDL, IDL and/or LDL) and thereby increased plasma concentrations of these. In familial hypercholesterolemia (FH), abnormal interaction is due to mutations in the
A, Nohara, H, Mabuchi
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Structural heterogeneity of apolipoprotein B‐100

The FEBS Journal
Cardiovascular disease is a major cause of human morbidity and mortality. Drug strategies for the prevention of the disease are largely centered on the interaction of low‐density lipoprotein receptor (LDLR) with the apolipoprotein B‐100 (apoB‐100) protein on low‐density lipoprotein (LDL). Recently, the structure of apoB‐100 on LDL was determined in the
Altaira D. Dearborn, Alan T. Remaley, Joseph Marcotrigiano   +2 more
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The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles

Atherosclerosis, 2010
The LPA I4399M (rs3798220) single nucleotide polymorphism (SNP) is associated with increased plasma levels of Lp(a) and advanced coronary artery disease (CAD). We hypothesized that carriers of the Met allele of the I4399M SNP would also have elevated levels of oxidized phospholipids (OxPL) on apoB (OxPL/apoB) particles.Plasma levels of Lp(a) and OxPL ...
Kiyohito, Arai, May M, Luke, Marlys L, Koschinsky, Elizabeth R, Miller, Clive R, Pullinger, Joseph L, Witztum, John P, Kane, Sotirios, Tsimikas   +7 more
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Apolipoprotein B-100 Hopkins (arginine4019----tryptophan). A new apolipoprotein B-100 variant in a family with premature atherosclerosis and hyperapobetalipoproteinemia.

JAMA, 1989
A 43-year-old woman with severe coronary artery disease and hyperapobetalipoproteinemia was heterozygous for an abnormal Msp I apolipoprotein B (APOB) gene fragment because of the absence of the MspI site around codon 4046 in exon 29 of the APOB gene.
J A, Ladias, P O, Kwiterovich, H H, Smith, M, Miller, P S, Bachorik, T, Forte, A J, Lusis, S E, Antonarakis   +7 more
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Haplotype analysis of apolipoprotein B-100 in subjects with familial defective apolipoprotein B-100

2002
Obiteljska pogreška u strukturi apolipoproteina B-100 je autosomno dodominantni premećaj zbog mutacije R3500Q gena za apolipoprotein B. Skupljeni su uzorci krvi 1489 ispitanika s hiperkolesterolemijom i/ili bolešću koronarnih arterija. Restrikcijskom izotipizacijom analiziran je ulomak DNA koji sadržava kodon 3500 gena za apo B.
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Familial defective apolipoprotein B-100 in Slovakia: are differences in prevalence of familial defective apolipoprotein B-100 explained by ethnicity?

Atherosclerosis, 2007
The objective of this study was to examine frequency of familial defective apo-B-100 (FDB, R3500Q mutation) in probands with the phenotype of familial hypercholesterolemia (FH) and in the general population of 40-year-old subjects in Slovakia and to characterize their lipid and clinical criteria and to compare the frequency of FDB with other ...
Juraj, Gasparovic, Zuzana, Basistová, L'ubomíra, Fábryová, Ladislava, Wsólová, Branislav, Vohnout, Katarína, Raslová   +5 more
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[11] Isolation and characterization of apolipoprotein B-100

1986
Publisher Summary Two physically separable macromolecules carry the designation apolipoproteinB. The long recognized form of apoB, large apoB or B-100, is the predominant protein in LDL and the major apoB protein found in human VLDL. This chapter describes the isolation and characterization of apolipoprotein B-100.
Waldo R. Fisher, Verne N. Schumaker
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Structure-Function Relationships of Apolipoprotein B-100

1993
Apolipoprotein (apo) B-100 is a huge protein that has been difficult to study by traditional protein chemistry techniques. Other experimental approaches, such as investigations in cultured cells, and in human subjects with specific apoB mutations also have their limitations a novel approach using transgenic mice has yielded interesting information on ...
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Specific oxidation of apolipoprotein-B-100 by myeloperoxidase

2010
info:eu-repo/semantics ...
Delporte, Cédric, Van Antwerpen, Pierre, Zouaoui Boudjeltia, Karim, Noyon, Caroline, Calay, Damien, Reye, Florence, Rousseau, Alexandre, Raes, Martine, Vanhaeverbeek, Michel, Ducobu, Jean, Neve, Jean   +10 more
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5408038 Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides

Biotechnology Advances, 1996
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