Mipomersen, an Antisense Oligonucleotide to Apolipoprotein B-100, Reduces Lipoprotein(a) in Various Populations With Hypercholesterolemia: Results of 4 Phase III Trials [PDF]
Arterioscler Thromb Vasc Biol, 2015 R. Santos +5 more
semanticscholar +2 more sources
In vitro oxidative footprinting provides insight into apolipoprotein B‐100 structure in low‐density lipoprotein [PDF]
Proteomics, 2014 S. Chakraborty, Yang Cai, M. Tarr
semanticscholar +2 more sources
Immunotherapy With Tolerogenic Apolipoprotein B-100–Loaded Dendritic Cells Attenuates Atherosclerosis in Hypercholesterolemic Mice [PDF]
, 2011 BACKGROUND: Atherosclerosis is a chronic inflammatory disease characterized by a massive intimal accumulation of low-density lipoprotein that triggers chronic vascular inflammation with an autoimmune response to low-density lipoprotein components.
Andreas Hermansson +5 more
openalex +4 more sources
High-Dose Atorvastatin Reduces Total Plasma Levels of Oxidized Phospholipids and Immune Complexes Present on Apolipoprotein B-100 in Patients With Acute Coronary Syndromes in the MIRACL Trial [PDF]
Circulation, 2004 Sotirios Tsimikas +6 more
openalex +2 more sources
Rapid Diagnosis of Familial Defective Apolipoprotein B-100 [PDF]
Clinical Chemistry and Laboratory Medicine, 1991 A method is described for the rapid, economic and non-radioactive examination of DNA samples from hypercholesterolaemic patients for familial defective apolipoprotein B-100, using a modified polymerase chain reaction (PCR) protocol and restriction enzyme isoform genotyping.
Geisel, J. +3 more
openaire +4 more sources
Clinical Chemistry, 2020 BACKGROUND With increased interest in lipoprotein(a) (Lp[a]) concentration as a target for risk reduction and growing clinical evidence of its impact on cardiovascular disease (CVD) risk, rigorous analytical performance specifications (APS) and accuracy ...
N. Clouet-Foraison +9 more
semanticscholar +1 more source
Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein. [PDF]
Journal of Clinical Investigation, 1981 In the two genetic forms of abetalipoproteinemia described previously, recessive abetalipoproteinemia and homozygous hypobetalipoproteinemia, all lipoproteins that normally contain apolipoprotein B are absent from plasma. We describe here a new disorder in which normal low density and very low density lipoproteins are absent, but in which triglycerides
John P. Kane +4 more
openaire +3 more sources
KADAR APOLIPOPROTEIN B 100 SERUM PADA PENDERITA NEFROPATI DIABETIKUM [PDF]
, 2015 AbstrakPenelitian ini bertujuan untuk mengetahui kadar Apolipoprotein B 100 serum pada penderita nefropati diabetikum. Metode penelitian ini dengan desain cross sectional yang bersifat deskriptif analitik.
Decroli, Eva
core +6 more sources
Characterization and quantitation of apolipoprotein B-100 by capillary electrophoresis [PDF]
Journal of Lipid Research, 1998 The interaction of low density lipoproteins (LDL) with different surfactants was studied by capillary electrophoresis (CE) and sucrose density gradient ultracentrifugation as part of developing a method for quantitation of apoB-100 in serum. A mixture of surfactants consisting of 70% sodium dodecyl sulfate (SDS), 25% sodium myristyl sulfate, and 5 ...
Ronald D. Macfarlane +3 more
openaire +4 more sources
Degradation of human apolipoprotein B‐100 by apolipoprotein(a)
FEBS Letters, 1993 Human plasma low density lipoproteine (LDL) contain a very high molecular weight protein termed apoB‐100 (M r = 550,000). In many samples of LDL, minor components designated as apoB‐74 (M r = 407,000) and apoB‐26 (M r = 145,000) are present. It has been shown that they can arise as a result of proteolytic degradation of apoB‐100.
V.V. Tertov, T.M. Chulkova
openaire +3 more sources