Results 11 to 20 of about 623 (213)

Apolipoprotein[a] secretion from hepatoma cells is regulated in a size-dependent manner by alterations in disulfide bond formation

Journal of Lipid Research, 2003
Apolipoprotein[a] (apo[a]) is a large disulfide linked glycoprotein synthesized by hepatocytes. We have examined the role of disulfide bond formation in the processing of apo[a] using human and rat hepatoma cells expressing apo[a] isoforms containing ...
Fatiha Nassir, Yan Xie, Nicholas O. Davidson   +2 more
doaj   +1 more source

PPARα deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins

Journal of Lipid Research, 2001
This study investigates the importance of peroxisome proliferator activated receptor α (PPARα) for serum apolipoprotein B (apoB) levels and hepatic secretion of apoB-containing lipoproteins.
Daniel Lindén, Mikael Alsterholm, Håkan Wennbo, Jan Oscarsson   +3 more
doaj   +1 more source

Key intestinal genes involved in lipoprotein metabolism are downregulated in dyslipidemic men with insulin resistance

Journal of Lipid Research, 2014
Insulin resistance (IR) is associated with elevated plasma levels of triglyceride-rich lipoproteins (TRLs) of intestinal origin. However, the mechanisms underlying the overaccumulation of apolipoprotein (apo)B-48-containing TRLs in individuals with IR ...
Patrick Couture, André J. Tremblay, Isabelle Kelly, Valéry Lemelin, Arnaud Droit, Benoît Lamarche   +5 more
doaj   +1 more source

KADAR APOLIPOPROTEIN B 100 SERUM PADA PENDERITA NEFROPATI DIABETIKUM

Majalah Kedokteran Andalas, 2015
AbstrakPenelitian ini bertujuan untuk mengetahui kadar Apolipoprotein B 100 serum pada penderita nefropati diabetikum. Metode penelitian ini dengan desain cross sectional yang bersifat deskriptif analitik.
Eva Decroli
doaj   +1 more source

A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma1[S]

Journal of Lipid Research, 2019
Atherosclerosis is associated with increased lipid peroxidation, leading to generation of multiple oxidation-specific epitopes (OSEs), contributing to the pathogenesis of atherosclerosis and its clinical manifestation. Oxidized cholesteryl esters (OxCEs)
Ayelet Gonen, Soo-Ho Choi, Phuong Miu, Colin Agatisa-Boyle, Daniel Acks, Angela M. Taylor, Coleen A. McNamara, Sotirios Tsimikas, Joseph L. Witztum, Yury I. Miller   +9 more
doaj   +1 more source

Metabolism of apoB lipoproteins of intestinal and hepatic origin during constant feeding of small amounts of fat

Journal of Lipid Research, 2006
We aimed to identify mechanisms by which apolipoprotein B-48 (apoB-48) could have an atherogenic role by simultaneously studying the metabolism of postprandial apoB-48 and apoB-100 lipoproteins.
Chunyu Zheng, Katsunori Ikewaki, Brian W. Walsh, Frank M. Sacks   +3 more
doaj   +1 more source

Evaluación de las concentraciones de lípidos y apoproteínas A-I y B-100 en un grupo de escolares de cinco departamentos del centro-oriente de Colombia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Existe evidencia sobre variaciones en las concentraciones de lípidos y apoproteínas en los niños asociados a cambios fisiológicos o al medio ambiente, este último puede inducir alteraciones futuras en los lípidos. Objetivo.
Elpidia Poveda, Ney Callas, César Baracaldo, Carlina Castillo, Patricia Hernández, Martha Guerra   +5 more
doaj   +1 more source

Identification of autoantibodies in human plasma recognizing an apoB-100 LDL receptor binding site peptide

Journal of Lipid Research, 2006
The aim of this study was to test the hypothesis that autoantibodies recognize amino acid sequences in the LDL receptor binding region of apolipoprotein B-100 (apoB-100). Autoantibodies against an unmodified or malondialdehyde (MDA)-modified LDL receptor
Gunilla Nordin Fredrikson, Göran Berglund, Ragnar Alm, Jan-Åke Nilsson, Prediman K. Shah, Jan Nilsson   +5 more
doaj   +1 more source

Identification of disulfide-linked apolipoprotein species in human lipoproteins

Journal of Lipid Research, 1993
We wished to determine whether apolipoprotein C-IIToronto, a mutant form of apolipoprotein C-II that contains a C-terminal cysteine residue, exists as a monomeric species or as multiple disulfide-linked species in plasma lipoproteins.
PW Connelly, GF Maguire, C Vezina, RA Hegele, JA Little   +4 more
doaj   +1 more source

The molecular basis of truncated forms of apolipoprotein B in a kindred with compound heterozygous hypobetalipoproteinemia.

Journal of Lipid Research, 1989
Krul et al. (1) have identified two truncated species of apolipoprotein B-100 in a kindred with familial hypobetalipoproteinemia. Five family members were identified who produce either one or both of two truncated apolipoprotein B-100 proteins estimated ...
P Talmud, L King-Underwood, E Krul, G Schonfeld, S Humphries   +4 more
doaj   +1 more source