Results 11 to 20 of about 92,925 (293)

KADAR APOLIPOPROTEIN B 100 SERUM PADA PENDERITA NEFROPATI DIABETIKUM

Majalah Kedokteran Andalas, 2015
AbstrakPenelitian ini bertujuan untuk mengetahui kadar Apolipoprotein B 100 serum pada penderita nefropati diabetikum. Metode penelitian ini dengan desain cross sectional yang bersifat deskriptif analitik.
Eva Decroli
doaj   +3 more sources

Familial Defective Apolipoprotein B-100 in 12 Subjects and Their Kindred [PDF]

Clinical Chemistry and Laboratory Medicine, 1992
Twelve unrelated subjects with heterozygous familial defective apolipoprotein B-100 were identified in a group of 252 patients with type IIa hypercholesterolaemia. Approximately 5% of hypercholesterolaemia can be explained by this mutation in the collective studied.
Geisel, J., Schleifenbaum, T., Oette, K., Weisshaar, Bernd   +3 more
openaire   +5 more sources

Human Placenta Secretes Apolipoprotein B-100-containing Lipoproteins [PDF]

Journal of Biological Chemistry, 2004
Supply of lipids from the mother is essential for fetal growth and development. In mice, disruption of yolk sac cell secretion of apolipoprotein (apo) B-containing lipoproteins results in embryonic lethality. In humans, the yolk sac is vestigial. Nutritional functions are instead established very early during pregnancy in the placenta.
Munk-Madsen, Eva, Lindegaard, Marie Louise Skakkebæk, Andersen, Claus B, Damm, Peter, Nielsen, Lars B   +4 more
openaire   +4 more sources

High prevalence of familial defective apolipoprotein B-100 in Switzerland. [PDF]

Journal of Lipid Research, 1994
Familial defective apolipoprotein B-100 (FDB) is caused by a single G-to-A substitution at nucleotide 10,708 leading to an arginine to glutamine change at amino acid 3,500 of the apolipoprotein B-100 and thus, a reduced binding of the apolipoprotein B to
A R Miserez, R Laager, N Chiodetti, U Keller   +3 more
doaj   +2 more sources

Oxidative events cause degradation of apoB-100 but not of apo[a] and facilitate enzymatic cleavage of both proteins

Journal of Lipid Research, 2001
Lipoprotein [a] (Lp[a]) contains equimolar amounts of apoB-100 and apolipoprotein [a] (apo[a]). Both proteins are amenable to degradation in vivo by mechanisms yet to be clearly defined.
Celina Edelstein, Kei Nakajima, Ditta Pfaffinger, Angelo M. Scanu   +3 more
doaj   +1 more source

Multiple tandem splicing silencer elements suppress aberrant splicing within the long exon 26 of the human Apolipoprotein B gene. [PDF]

, 2013
: BACKGROUND: Apolipoprotein B (APOB) is an integral component of the chylomicron and the atherogenic lipoproteins LDL and Lp(a). Exon 26 of the APOB pre-mRNA is unusually long at 7,572 nt and is constitutively spliced.
Srirangalingam, U, Navaratnam, N, Chew, SL, Norman, D, Khoo, B, Akker, SA   +5 more
core   +1 more source

Apolipoprotein[a] secretion from hepatoma cells is regulated in a size-dependent manner by alterations in disulfide bond formation

Journal of Lipid Research, 2003
Apolipoprotein[a] (apo[a]) is a large disulfide linked glycoprotein synthesized by hepatocytes. We have examined the role of disulfide bond formation in the processing of apo[a] using human and rat hepatoma cells expressing apo[a] isoforms containing ...
Fatiha Nassir, Yan Xie, Nicholas O. Davidson   +2 more
doaj   +1 more source

PPARα deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins

Journal of Lipid Research, 2001
This study investigates the importance of peroxisome proliferator activated receptor α (PPARα) for serum apolipoprotein B (apoB) levels and hepatic secretion of apoB-containing lipoproteins.
Daniel Lindén, Mikael Alsterholm, Håkan Wennbo, Jan Oscarsson   +3 more
doaj   +1 more source

Key intestinal genes involved in lipoprotein metabolism are downregulated in dyslipidemic men with insulin resistance

Journal of Lipid Research, 2014
Insulin resistance (IR) is associated with elevated plasma levels of triglyceride-rich lipoproteins (TRLs) of intestinal origin. However, the mechanisms underlying the overaccumulation of apolipoprotein (apo)B-48-containing TRLs in individuals with IR ...
Patrick Couture, André J. Tremblay, Isabelle Kelly, Valéry Lemelin, Arnaud Droit, Benoît Lamarche   +5 more
doaj   +1 more source

A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma1[S]

Journal of Lipid Research, 2019
Atherosclerosis is associated with increased lipid peroxidation, leading to generation of multiple oxidation-specific epitopes (OSEs), contributing to the pathogenesis of atherosclerosis and its clinical manifestation. Oxidized cholesteryl esters (OxCEs)
Ayelet Gonen, Soo-Ho Choi, Phuong Miu, Colin Agatisa-Boyle, Daniel Acks, Angela M. Taylor, Coleen A. McNamara, Sotirios Tsimikas, Joseph L. Witztum, Yury I. Miller   +9 more
doaj   +1 more source