Results 21 to 30 of about 92,925 (293)

Metabolism of apoB lipoproteins of intestinal and hepatic origin during constant feeding of small amounts of fat

Journal of Lipid Research, 2006
We aimed to identify mechanisms by which apolipoprotein B-48 (apoB-48) could have an atherogenic role by simultaneously studying the metabolism of postprandial apoB-48 and apoB-100 lipoproteins.
Chunyu Zheng, Katsunori Ikewaki, Brian W. Walsh, Frank M. Sacks   +3 more
doaj   +1 more source

Evaluación de las concentraciones de lípidos y apoproteínas A-I y B-100 en un grupo de escolares de cinco departamentos del centro-oriente de Colombia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Existe evidencia sobre variaciones en las concentraciones de lípidos y apoproteínas en los niños asociados a cambios fisiológicos o al medio ambiente, este último puede inducir alteraciones futuras en los lípidos. Objetivo.
Elpidia Poveda, Ney Callas, César Baracaldo, Carlina Castillo, Patricia Hernández, Martha Guerra   +5 more
doaj   +1 more source

Identification of autoantibodies in human plasma recognizing an apoB-100 LDL receptor binding site peptide

Journal of Lipid Research, 2006
The aim of this study was to test the hypothesis that autoantibodies recognize amino acid sequences in the LDL receptor binding region of apolipoprotein B-100 (apoB-100). Autoantibodies against an unmodified or malondialdehyde (MDA)-modified LDL receptor
Gunilla Nordin Fredrikson, Göran Berglund, Ragnar Alm, Jan-Åke Nilsson, Prediman K. Shah, Jan Nilsson   +5 more
doaj   +1 more source

Identification of disulfide-linked apolipoprotein species in human lipoproteins

Journal of Lipid Research, 1993
We wished to determine whether apolipoprotein C-IIToronto, a mutant form of apolipoprotein C-II that contains a C-terminal cysteine residue, exists as a monomeric species or as multiple disulfide-linked species in plasma lipoproteins.
PW Connelly, GF Maguire, C Vezina, RA Hegele, JA Little   +4 more
doaj   +1 more source

The molecular basis of truncated forms of apolipoprotein B in a kindred with compound heterozygous hypobetalipoproteinemia.

Journal of Lipid Research, 1989
Krul et al. (1) have identified two truncated species of apolipoprotein B-100 in a kindred with familial hypobetalipoproteinemia. Five family members were identified who produce either one or both of two truncated apolipoprotein B-100 proteins estimated ...
P Talmud, L King-Underwood, E Krul, G Schonfeld, S Humphries   +4 more
doaj   +1 more source

Apolipoprotein AIV gene variant S347 is associated with increased risk of coronary heart disease and lower plasma apolipoprotein AIV levels [PDF]

, 2003
The impact of common variants in the apolipoprotein gene cluster (APOC3-A4-A5) on prospective coronary heart disease (CHD) risk was examined in healthy UK men. Of the 2808 men followed over 9 years, 187 had a clinically defined CHD event.
Hawe, E., Miller, G.J., Hawe, Emma, Nicaud, V., Wong, W.-M.R., Wong, Wai-man R., Humphries, S.E., Li, Lai K., Li, L.K., Talmud, P.J., Nicaud, Viviane, Miller, George J., Pennacchio, Len A., Talmud, Philippa J., Pennacchio, L.A., Humphries, Steve E.   +15 more
core   +1 more source

Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice

Journal of Lipid Research, 1999
Over the past 10 years, many laboratories have investigated lipid metabolism and atherogenesis with a variety of transgenic and gene knockout mouse models.
Constance H. Zlot, Laura M. Flynn, Murielle M. Véniant, Edward Kim, Martin Raabe, Sally P.A. McCormick, Patricia Ambroziak, Leslie M. McEvoy, Stephen G. Young   +8 more
doaj   +1 more source

Effect of Early Enteral Feeding on Apolipoprotein AI Levels and High-Density Lipoprotein Heterogeneity in Preterm Infants [PDF]

, 2001
Background/Aim: We have previously shown that infants receiving total parenteral nutrition have low apolipoprotein Al levels which are associated with high-density lipoprotein (HDL) class distributions as in lecithin:cholesterol acyltransferase ...
Berthold Koletzkob, Koletzko, Berthold, Yvonne Göbelb, Genzel-Boroviczény, Orsolya, Göbel, Yvonne, Orsolya Genzel-boroviczénya   +5 more
core   +1 more source

Rapid turnover of apolipoprotein C-III-containing triglyceride-rich lipoproteins contributing to the formation of LDL subfractionss⃞

Journal of Lipid Research, 2007
The atherogenicity theory for triglyceride-rich lipoproteins (TRLs; VLDL + intermediate density lipoprotein) generally cites the action of apolipoprotein C-III (apoC-III), a component of some TRLs, to retard their metabolism in plasma.
Zheng Chunyu, Khoo Christina, Ikewaki Katsunori, Frank M. Sacks   +3 more
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source